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Curr Treat Options Gastroenterol. 2001 Apr;4(2):149-162. doi: 10.1007/s11938-001-0027-1.

Small Intestinal Infections.

Current treatment options in gastroenterology

Saurabh Mehandru, Edmund J. Bini

Affiliations

  1. Division of Gastroenterology 111D, Veterans Administration New York Harbor Healthcare System, 423 East 23rd Street, New York, NY 10010, USA. [email protected]

PMID: 11469973 DOI: 10.1007/s11938-001-0027-1

Abstract

The differential diagnosis of small intestinal infections is broad, making the identification and management of these disorders challenging. The majority of cases of acute diarrhea are self-limited and do not require diagnostic evaluation or treatment. Most patients do not require specific therapy, and treatment should focus on fluid and electrolyte replacement. In patients with severe, persistent, or chronic diarrhea, a careful medical history and routine stool testing are helpful in determining the cause. Pathogen-specific therapy should be given in patients in whom a pathogen is identified. In those without an identifiable pathogen, antidiarrheal agents are helpful in reducing the number of bowel movements and preventing further dehydration. Endoscopy may be helpful in patients with severe diarrhea and a negative stool evaluation, particularly in HIV-infected patients with chronic diarrhea. Surgery has a limited role in the management of small intestinal infections, but may be lifesaving in patients with intestinal perforation or small bowel obstruction.

References

  1. Am J Med. 1999 Jun;106(6):670-6 - PubMed
  2. Drugs. 1993;45 Suppl 3:119-24 - PubMed
  3. Ann Intern Med. 1998 Dec 1;129(11):875-7 - PubMed
  4. J Infect Dis. 1998 Dec;178(6):1571-8 - PubMed
  5. Am J Gastroenterol. 1993 Jul;88(7):989-99 - PubMed
  6. J Antimicrob Chemother. 1996 Mar;37(3):575-81 - PubMed
  7. Ann Intern Med. 1993 Nov 1;119(9):924-35 - PubMed
  8. Mil Med. 1984 Jan;149(1):12-6 - PubMed
  9. N Engl J Med. 1986 Jul 10;315(2):87-90 - PubMed
  10. Clin Infect Dis. 1999 May;28(5):1049-56 - PubMed
  11. Arch Med Res. 2000 Jan-Feb;31(1):3-14 - PubMed
  12. Drugs. 1988;36 Suppl 4:80-90 - PubMed
  13. J Pediatr. 1984 Feb;104(2):308-11 - PubMed
  14. Br J Surg. 1991 Aug;78(8):952-4 - PubMed
  15. Contrib Microbiol Immunol. 1995;13:172-4 - PubMed
  16. J Infect Dis. 1998 Sep;178(3):900-3 - PubMed
  17. Am J Trop Med Hyg. 1995 Feb;52(2):162-5 - PubMed
  18. Lancet. 1992 Jul 4;340(8810):28-33 - PubMed
  19. Gastroenterology. 2000 Feb;118(2 Suppl 1):S48-67 - PubMed
  20. Am J Trop Med Hyg. 1996 Nov;55(5):477-81 - PubMed
  21. Arch Intern Med. 1998 May 11;158(9):957-69 - PubMed
  22. J Infect Dis. 1994 May;169(5):1076-9 - PubMed
  23. Trans R Soc Trop Med Hyg. 1994 Sep-Oct;88(5):585-9 - PubMed
  24. Gastroenterology. 1985 Jun;88(6):1867-73 - PubMed
  25. Antimicrob Agents Chemother. 1997 Jul;41(7):1504-7 - PubMed
  26. J Clin Pathol. 1992 Sep;45(9):806-11 - PubMed
  27. J Clin Gastroenterol. 2000 Jun;30(4):414-9 - PubMed
  28. N Engl J Med. 1989 Jul 6;321(1):16-24 - PubMed
  29. Lancet. 1996 Aug 3;348(9023):296-300 - PubMed
  30. J Infect. 1985 Jan;10(1):65-7 - PubMed
  31. J Infect Dis. 2000 May;181(5):1661-6 - PubMed
  32. Ann Intern Med. 1994 Nov 1;121(9):654-7 - PubMed
  33. Gastroenterology. 1996 Dec;111(6):1724-52 - PubMed
  34. Am J Gastroenterol. 1997 Nov;92(11):1962-75 - PubMed
  35. Antimicrob Agents Chemother. 2000 Feb;44(2):441-3 - PubMed
  36. Am J Med. 1994 Aug;97(2):135-44 - PubMed
  37. Vaccine. 1995 May;13(7):691-4 - PubMed
  38. BMJ. 1990 Jun 23;300(6740):1619-21 - PubMed
  39. Clin Infect Dis. 1998 Apr;26(4):781-803; quiz 804-5 - PubMed
  40. Am J Med. 1992 Feb;92(2):225-7 - PubMed
  41. N Engl J Med. 1996 Aug 8;335(6):392-8 - PubMed
  42. Gastroenterol Clin North Am. 1997 Jun;26(2):259-90 - PubMed
  43. J Infect Dis. 1994 Aug;170(2):419-24 - PubMed
  44. J Infect Dis. 1998 May;177(5):1373-7 - PubMed
  45. J Infect Dis. 1995 Sep;172(3):622-8 - PubMed
  46. Gastroenterology. 1980 Jun;78(6):1495-9 - PubMed
  47. Ann Intern Med. 1987 Feb;106(2):216-20 - PubMed
  48. Am J Med. 1997 Sep;103(3):223-32 - PubMed
  49. J Antimicrob Chemother. 1992 Aug;30(2):221-8 - PubMed
  50. J Infect Dis. 1998 Feb;177(2):515-8 - PubMed
  51. Ann Intern Med. 1992 Aug 1;117(3):202-8 - PubMed
  52. Antimicrob Agents Chemother. 1996 Jan;40(1):86-91 - PubMed
  53. Clin Infect Dis. 1999 Jul;29(1):125-33 - PubMed
  54. Med Lett Drugs Ther. 1998 Jan 2;40(1017):1-12 - PubMed
  55. JAMA. 1987 Mar 13;257(10):1347-50 - PubMed
  56. Am J Med. 1984 May;76(5):794-8 - PubMed
  57. Am J Gastroenterol. 1999 Dec;94(12):3553-9 - PubMed
  58. Ann Intern Med. 2000 Jun 6;132(11):885-8 - PubMed
  59. Gastrointest Endosc Clin N Am. 1998 Oct;8(4):857-67 - PubMed
  60. Public Health Rep. 1988 Mar-Apr;103(2):107-15 - PubMed
  61. Southeast Asian J Trop Med Public Health. 1991 Dec;22 Suppl:153-7 - PubMed

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