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Carfagna P, Pistella E, Paravati V, et al. Arthritis as a rare side effect of phenytoin therapy. Eur J Intern Med. 2001;12(5):448-450doi: 10.1016/s0953-6205(01)00152-2.
Carfagna, P., Pistella, E., Paravati, V., & Serra, P. (2001). Arthritis as a rare side effect of phenytoin therapy. European journal of internal medicine, 12(5), 448-450. https://doi.org/10.1016/s0953-6205(01)00152-2
Carfagna, P, et al. "Arthritis as a rare side effect of phenytoin therapy." European journal of internal medicine vol. 12,5 (2001): 448-450. doi: https://doi.org/10.1016/s0953-6205(01)00152-2
Carfagna P, Pistella E, Paravati V, Serra P. Arthritis as a rare side effect of phenytoin therapy. Eur J Intern Med. 2001 Sep;12(5):448-450. doi: 10.1016/s0953-6205(01)00152-2. PMID: 11557332.
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Eur J Intern Med. 2001 Sep;12(5):448-450. doi: 10.1016/s0953-6205(01)00152-2.

Arthritis as a rare side effect of phenytoin therapy.

European journal of internal medicine

P Carfagna, E Pistella, V Paravati, P Serra

Affiliations

  1. Clinica Medica 3, Department of Clinical Medicine, University of Rome 'La Sapienza', Rome, Italy

PMID: 11557332 DOI: 10.1016/s0953-6205(01)00152-2

Abstract

Anticonvulsant hypersensitivity syndrome is an uncommon side effect of phenytoin. It is characterized by fever, skin reactions, lymphadenopathy, and severe multiorgan involvement. Atypical clinical features have rarely been described. We observed a unique case of anticonvulsant hypersensitivity syndrome in a 77-year-old woman in whom fever and monoarthritis were the main clinical features. Symptoms dramatically subsided after phenytoin withdrawal.

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