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Hsia HH, Jessup ML, Marchlinski FE. Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?. Curr Control Trials Cardiovasc Med. 2000;1(2):98-101doi: 10.1186/cvm-1-2-098.
Hsia, H. H., Jessup, M. L., & Marchlinski, F. E. (2000). Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?. Current controlled trials in cardiovascular medicine, 1(2), 98-101. https://doi.org/10.1186/cvm-1-2-098
Hsia, Henry H, et al. "Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?." Current controlled trials in cardiovascular medicine vol. 1,2 (2000): 98-101. doi: https://doi.org/10.1186/cvm-1-2-098
Hsia HH, Jessup ML, Marchlinski FE. Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?. Curr Control Trials Cardiovasc Med. 2000;1(2):98-101. doi: 10.1186/cvm-1-2-098. PMID: 11714420; PMCID: PMC59609.
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Curr Control Trials Cardiovasc Med. 2000;1(2):98-101. doi: 10.1186/cvm-1-2-098.

Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?.

Current controlled trials in cardiovascular medicine

Henry H Hsia, Mariell L Jessup, Francis E Marchlinski

Affiliations

  1. University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA. [email protected]

PMID: 11714420 PMCID: PMC59609 DOI: 10.1186/cvm-1-2-098

Abstract

Sudden death is a major cause of mortality in patients with ventricular dysfunction. The highest risk occurs among patients with less severe functional impairment. Current methods of risk stratification are inadequate, and a rational therapy for prevention of sudden death is not available. The implantable cardioverter-defibrillator (ICD) has proven to be more effective than drugs in reducing sudden-death risk in some subsets of patients. Empiric ICD therapy, targeting the general population with mild to moderate heart failure, will maximize the impact of such a strategy to prevent sudden death and improve long-term survival.

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