Display options
Cite
Weber L. Multi-component reactions and evolutionary chemistry. Drug Discov Today. 2002;7(2):143-7doi: 10.1016/s1359-6446(01)02090-6.
Weber, L. (2002). Multi-component reactions and evolutionary chemistry. Drug discovery today, 7(2), 143-7. https://doi.org/10.1016/s1359-6446(01)02090-6
Weber, Lutz. "Multi-component reactions and evolutionary chemistry." Drug discovery today vol. 7,2 (2002): 143-7. doi: https://doi.org/10.1016/s1359-6446(01)02090-6
Weber L. Multi-component reactions and evolutionary chemistry. Drug Discov Today. 2002 Jan 15;7(2):143-7. doi: 10.1016/s1359-6446(01)02090-6. PMID: 11790626.
Copy Download .nbib Format: NLM
Share it on

Drug Discov Today. 2002 Jan 15;7(2):143-7. doi: 10.1016/s1359-6446(01)02090-6.

Multi-component reactions and evolutionary chemistry.

Drug discovery today

Lutz Weber

Affiliations

  1. Morphochem, Gmunderstr. 37, D-81379 München, Germany. [email protected]

PMID: 11790626 DOI: 10.1016/s1359-6446(01)02090-6

Abstract

Multi-component reactions (MCRs) provide a new approach towards the efficient synthesis of diverse compounds and compound libraries. MCRs are evolving from being purely a chemistry curiosity to being recognized as having increasing relevance for drug discovery in terms of lead discovery and optimization. The combination of MCR-type chemistry-planning with evolutionary in silico and in vitro prediction of drug potential or biological properties is a new and powerful tool in drug discovery.

MeSH terms

Publication Types