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Acher R, Chauvet J, Chauvet M. Molecular evolution of the neurohypophysial hormones: The active peptides of a primitive bony fish Polypterus bichir. FEBS Lett. 1970;11(5):332-335doi: 10.1016/0014-5793(70)80561-0.
Acher, R., Chauvet, J., & Chauvet, M. (1970). Molecular evolution of the neurohypophysial hormones: The active peptides of a primitive bony fish Polypterus bichir. FEBS letters, 11(5), 332-335. https://doi.org/10.1016/0014-5793(70)80561-0
Acher, R, et al. "Molecular evolution of the neurohypophysial hormones: The active peptides of a primitive bony fish Polypterus bichir." FEBS letters vol. 11,5 (1970): 332-335. doi: https://doi.org/10.1016/0014-5793(70)80561-0
Acher R, Chauvet J, Chauvet M. Molecular evolution of the neurohypophysial hormones: The active peptides of a primitive bony fish Polypterus bichir. FEBS Lett. 1970 Dec 18;11(5):332-335. doi: 10.1016/0014-5793(70)80561-0. PMID: 11945519.
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FEBS Lett. 1970 Dec 18;11(5):332-335. doi: 10.1016/0014-5793(70)80561-0.

Molecular evolution of the neurohypophysial hormones: The active peptides of a primitive bony fish Polypterus bichir.

FEBS letters

R Acher, J Chauvet, M -T. Chauvet

Affiliations

  1. Laboratory of Biological Chemistry, Faculty of Science, Paris, France

PMID: 11945519 DOI: 10.1016/0014-5793(70)80561-0

Abstract

Neurohypophysial hormones have been so far identified in Neopterygii and Crossopterygii but not in species of the bird sub-class of bony fishes, the Palaeopterygii. Isolation and chemical characterization of the active principles of a primitive bony fish, Polypterus bichir, have been performed. Isotocin (Ser(4)-Ile(8)-oxytocin) and arginine vasotocin (Arg(8)-oxytocin) have been identified. Because the same peptides were found in the recent Neopterygii, it can be deduced that neurohypophysial hormones have displayed a peculiar stability in the course of the evolution of bony fishes. However isotocin and vasotocin are replaced by oxytocin and vasopressins in mammals and therefore might be regarded as "old" molecules.

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