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Klee MS, Blumberg LM. Theoretical and practical aspects of fast gas chromatography and method translation. J Chromatogr Sci. 2002;40(5):234-47doi: 10.1093/chromsci/40.5.234.
Klee, M. S., & Blumberg, L. M. (2002). Theoretical and practical aspects of fast gas chromatography and method translation. Journal of chromatographic science, 40(5), 234-47. https://doi.org/10.1093/chromsci/40.5.234
Klee, Matthew S, and Blumberg, Leonid M. "Theoretical and practical aspects of fast gas chromatography and method translation." Journal of chromatographic science vol. 40,5 (2002): 234-47. doi: https://doi.org/10.1093/chromsci/40.5.234
Klee MS, Blumberg LM. Theoretical and practical aspects of fast gas chromatography and method translation. J Chromatogr Sci. 2002 May-Jun;40(5):234-47. doi: 10.1093/chromsci/40.5.234. PMID: 12049153.
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J Chromatogr Sci. 2002 May-Jun;40(5):234-47. doi: 10.1093/chromsci/40.5.234.

Theoretical and practical aspects of fast gas chromatography and method translation.

Journal of chromatographic science

Matthew S Klee, Leonid M Blumberg

Affiliations

  1. Agilent Technologies, Inc., Wilmington, DE 19808, USA.

PMID: 12049153 DOI: 10.1093/chromsci/40.5.234

Abstract

Interest in the development and implementation of fast gas chromatography (GC) methods continues to increase. Fast GC method development and validation can be simplified and more successful if a few key theoretical and practical concepts are kept in mind. Key concepts such as speed-optimized flow rate, optimal temperature-program rate, sample capacity, "cut the column", and principles of method translation are discussed.

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