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Seki K, Wakatsuki S, Hizawa K, et al. Multiple Endocrine Neoplasms in a Patient with AL Amyloidosis-Associated Plasma Cell Dyscrasia. Endocr Pathol. 1997;8(2):153-160doi: 10.1007/BF02739944.
Seki, K., Wakatsuki, S., Hizawa, K., Hasegawa, T., Fujinaka, Y., Yokogoshi, H., Saito, S., & Sano, T. (1997). Multiple Endocrine Neoplasms in a Patient with AL Amyloidosis-Associated Plasma Cell Dyscrasia. Endocrine pathology, 8(2), 153-160. https://doi.org/10.1007/BF02739944
Seki, Kunihiko, et al. "Multiple Endocrine Neoplasms in a Patient with AL Amyloidosis-Associated Plasma Cell Dyscrasia." Endocrine pathology vol. 8,2 (1997): 153-160. doi: https://doi.org/10.1007/BF02739944
Seki K, Wakatsuki S, Hizawa K, Hasegawa T, Fujinaka Y, Yokogoshi H, Saito S, Sano T. Multiple Endocrine Neoplasms in a Patient with AL Amyloidosis-Associated Plasma Cell Dyscrasia. Endocr Pathol. 1997;8(2):153-160. doi: 10.1007/BF02739944. PMID: 12114636.
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Endocr Pathol. 1997;8(2):153-160. doi: 10.1007/BF02739944.

Multiple Endocrine Neoplasms in a Patient with AL Amyloidosis-Associated Plasma Cell Dyscrasia.

Endocrine pathology

Kunihiko Seki, Shingo Wakatsuki, Kazuo Hizawa, Tadashi Hasegawa, Yuichi Fujinaka, Hiroshi Yokogoshi, Shiro Saito, Toshiaki Sano

PMID: 12114636 DOI: 10.1007/BF02739944

Abstract

Reports on patients with systemic amyloidosis-associated plasma cell dyscrasia (PCD) who have multiple endocrine tumors are very rare. Here we describe such a case. The patient was a 74-yr-old man with amyloid light-chain (AL) amyloidosis-associated PCD who had a null-cell adenoma of the pituitary and a latent papillary carcinoma of the thyroid gland. as well as a tubular adenoma of the sigmoid colon. The amyloid protein deposits reacted with the antibody to the n-immunoglobulin light chain. Since PCD by itself may be a risk factor for the development of subsequent neoplasms, the careful clinical evaluation of PCD patients is recommended.

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