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Pérez Luna A, Ceschi MA, Bonin M, et al. Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores. J Org Chem. 2002;67(10):3522-4doi: 10.1021/jo011190e.
Pérez Luna, A., Ceschi, M. A., Bonin, M., Micouin, L., Husson, H. P., Gougeon, S., Estenne-Bouhtou, G., Marabout, B., Sevrin, M., & George, P. (2002). Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores. The Journal of organic chemistry, 67(10), 3522-4. https://doi.org/10.1021/jo011190e
Pérez Luna, A, et al. "Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores." The Journal of organic chemistry vol. 67,10 (2002): 3522-4. doi: https://doi.org/10.1021/jo011190e
Pérez Luna A, Ceschi MA, Bonin M, Micouin L, Husson HP, Gougeon S, Estenne-Bouhtou G, Marabout B, Sevrin M, George P. Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores. J Org Chem. 2002 May 17;67(10):3522-4. doi: 10.1021/jo011190e. PMID: 12003572.
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J Org Chem. 2002 May 17;67(10):3522-4. doi: 10.1021/jo011190e.

Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores.

The Journal of organic chemistry

A Pérez Luna, M-A Ceschi, M Bonin, L Micouin, H-P Husson, S Gougeon, G Estenne-Bouhtou, B Marabout, M Sevrin, P George

Affiliations

  1. Laboratoire de Chimie Thèrapeutique UMR 8638 associée au CNRS et à l'Université René Descartes Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France.

PMID: 12003572 DOI: 10.1021/jo011190e

Abstract

Catalytic asymmetric hydroboration can be successfully applied to meso bicyclic hydrazines. The resulting alcohols are of great synthetic interest and can lead in a straightforward manner to cyclopentanic diamino alcohols with good enantiomeric purity.

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