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Carlier SG, Coen VL, Sabaté M, et al. The role of intravascular ultrasound imaging in vascular brachytherapy. Int J Cardiovasc Intervent. 2000;3(1):3-12doi: 10.1080/14628840050516253.
Carlier, S. G., Coen, V. L., Sabaté, M., Kay, I. P., Ligthart, J. M., Van Der Giessen, W. J., Levendag, P. C., Bom, K., & Serruys, P. W. (2000). The role of intravascular ultrasound imaging in vascular brachytherapy. International journal of cardiovascular interventions, 3(1), 3-12. https://doi.org/10.1080/14628840050516253
Carlier, Stéphane G, et al. "The role of intravascular ultrasound imaging in vascular brachytherapy." International journal of cardiovascular interventions vol. 3,1 (2000): 3-12. doi: https://doi.org/10.1080/14628840050516253
Carlier SG, Coen VL, Sabaté M, Kay IP, Ligthart JM, Van Der Giessen WJ, Levendag PC, Bom K, Serruys PW. The role of intravascular ultrasound imaging in vascular brachytherapy. Int J Cardiovasc Intervent. 2000 Mar;3(1):3-12. doi: 10.1080/14628840050516253. PMID: 12470381.
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Int J Cardiovasc Intervent. 2000 Mar;3(1):3-12. doi: 10.1080/14628840050516253.

The role of intravascular ultrasound imaging in vascular brachytherapy.

International journal of cardiovascular interventions

Stéphane G Carlier, Véronique LMA Coen, Manel Sabaté, I Patrick Kay, Jurgen MR Ligthart, Willem J Van Der Giessen, Peter C Levendag, K Bom, Patrick W Serruys

Affiliations

  1. The Thoraxcenter, Heart Center, Department of Interventional Cardiology, Academisch Ziekenhuis Rotterdam-Dijkzigt and the Experimental Echocardiography Laboratory, Erasmus University, Rotterdam, The Netherlands.

PMID: 12470381 DOI: 10.1080/14628840050516253

Abstract

Intracoronary brachytherapy has recently emerged as a new therapy to prevent restenosis. Initial experimental work was achieved in animal models and the results were assessed by histomorphometry. Initial clinical trials used angiography to guide dosimetry and to assess efficacy. Intravascular ultrasound (IVUS) permits tomographic examination of the vessel wall, elucidating the true morphology of the lumen and transmural components, which cannot be investigated on the lumenogram obtained by angiography. This paper reviews the use of IVUS in the clinical studies of brachytherapy conducted to date. IVUS allows clinicians to make a thorough assessment of the remodeling of the vessel and appears to have a major role to play in facilitating understanding of the underlying mechanisms of action in this emerging field. The authors propose that state-of-the-art IVUS techniques should be employed to further knowledge of the mechanisms of action of brachytherapy in atherosclerotic human coronary arteries.

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