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Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2000 Sep;8(3):227-230.

[Progress in Study on MHC Structure and Function].

Zhongguo shi yan xue ye xue za zhi

[Article in Chinese]
Yuying Sun, Fanhua Kong, Yongzhi Xi

Affiliations

  1. Department of Immunology, Beijing Beitaiping Rood Hospital, Beijing 100039, China.

PMID: 12578688

Abstract

The MHC molecules were first discovered as major histocompatibility antigens. When their essential biological function as antigen-binding molecules and informers for T cells was unveiled, an explanation of why MHC also acts as major histocompatibility antigens was provided. When the antigen-binding cleft of MHC molecules was firstly clarified more than 10 years ago, the study of MHC structure and function has stepped into a prosperous new era, and many achievements have in this area have been achieved. This paper summarized the exciting progress in study on MHC structure and function in recent years.

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