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Genome Biol. 2003;4(4):R28. doi: 10.1186/gb-2003-4-4-r28. Epub 2003 Mar 25.

GoMiner: a resource for biological interpretation of genomic and proteomic data.

Genome biology

Barry R Zeeberg, Weimin Feng, Geoffrey Wang, May D Wang, Anthony T Fojo, Margot Sunshine, Sudarshan Narasimhan, David W Kane, William C Reinhold, Samir Lababidi, Kimberly J Bussey, Joseph Riss, J Carl Barrett, John N Weinstein

Affiliations

  1. Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

PMID: 12702209 PMCID: PMC154579 DOI: 10.1186/gb-2003-4-4-r28

Abstract

We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative and statistical output files and two useful visualizations. The first is a tree-like structure analogous to that in the AmiGO browser and the second is a compact, dynamically interactive 'directed acyclic graph'. Genes displayed in GoMiner are linked to major public bioinformatics resources.

References

  1. Biotechniques. 1999 Dec;27(6):1210-4, 1216-7 - PubMed
  2. Nat Genet. 2000 May;25(1):25-9 - PubMed
  3. Genomics. 2002 Feb;79(2):266-70 - PubMed
  4. Science. 1998 Oct 23;282(5389):628-9 - PubMed
  5. Genome Biol. 2003;4(1):R7 - PubMed
  6. Cancer Res. 2003 Mar 1;63(5):1000-11 - PubMed
  7. Genome Biol. 2003;4(4):R27 - PubMed
  8. Curr Opin Pharmacol. 2002 Aug;2(4):361-5 - PubMed

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