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Curr Treat Options Gastroenterol. 2003 Feb;6(1):13-16. doi: 10.1007/s11938-003-0028-3.

Current Insights in Whipple's Disease.

Current treatment options in gastroenterology

Mark C. Flemmer, Ronald W. Flenner

Affiliations

  1. Department of Internal Medicine, Eastern Virginia Medical School, Hofheimer Hall, 825 Fairfax Avenue, Norfolk, VA 23507-1912, USA. [email protected]

PMID: 12521567 DOI: 10.1007/s11938-003-0028-3

Abstract

Therapy for Whipple's disease should be continued for a minimum of 1 year, and the regimen should include an agent or agents that achieve acceptable concentrations in the central nervous system, given the likelihood of recurrence at this site. Clinical follow-up of proven cases of Whipple's disease should be conducted for a minimum of 10 years after discontinuation of therapy, given the potential for late relapses. Polymerase chain reaction analysis is preferred rather than endoscopy when evaluating for disease recurrence.

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