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van der Linden HJ, Herber S, Olthuis W, et al. Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis. Analyst. 2003;128(4):325-31doi: 10.1039/b210140h.
van der Linden, H. J., Herber, S., Olthuis, W., & Bergveld, P. (2003). Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis. The Analyst, 128(4), 325-31. https://doi.org/10.1039/b210140h
van der Linden, Heiko J, et al. "Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis." The Analyst vol. 128,4 (2003): 325-31. doi: https://doi.org/10.1039/b210140h
van der Linden HJ, Herber S, Olthuis W, Bergveld P. Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis. Analyst. 2003 Apr;128(4):325-31. doi: 10.1039/b210140h. PMID: 12741636.
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Analyst. 2003 Apr;128(4):325-31. doi: 10.1039/b210140h.

Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis.

The Analyst

Heiko J van der Linden, Sebastiaan Herber, Wouter Olthuis, Piet Bergveld

Affiliations

  1. Chair of Biosensors, Faculty of Electrical Engineering, Mesa+ Research Institute, Twente University, Drienerlolaan 5, 7500AE Enschede, The Netherlands. [email protected]

PMID: 12741636 DOI: 10.1039/b210140h

Abstract

In this tutorial review the use of stimulus-sensitive hydrogels as sensors and actuators for (micro)analytical applications is discussed. The first part of the article is aimed at making the reader familiar with stimulus-sensitive hydrogels, their chemical composition and their chemo-physical behavior. The prior art in the field, that comprises a number of sensors ranging from metal ion-sensitive sensors to antigen-sensitive sensors and a few actuators, is also treated in this part. The second part of the article focusses on the use of stimulus-sensitive hydrogels for microsensors and microactuators as well as their application in micro total analysis systems. The benefits of stimulus-sensitive hydrogels, their miniaturisation and the use of 365 nm UV-photolithography as a fast economical manufacturing technique are discussed.

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