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Bourne TH, Lawton F, Leather A, et al. Use of intracavity saline instillation and transvaginal ultrasonography to detect tamoxifen-associated endometrial polyps. Ultrasound Obstet Gynecol. 1994;4(1):73-5doi: 10.1046/j.1469-0705.1994.04010073.x.
Bourne, T. H., Lawton, F., Leather, A., Granberg, S., Campbell, S., & Collins, W. P. (1994). Use of intracavity saline instillation and transvaginal ultrasonography to detect tamoxifen-associated endometrial polyps. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 4(1), 73-5. https://doi.org/10.1046/j.1469-0705.1994.04010073.x
Bourne, T H, et al. "Use of intracavity saline instillation and transvaginal ultrasonography to detect tamoxifen-associated endometrial polyps." Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology vol. 4,1 (1994): 73-5. doi: https://doi.org/10.1046/j.1469-0705.1994.04010073.x
Bourne TH, Lawton F, Leather A, Granberg S, Campbell S, Collins WP. Use of intracavity saline instillation and transvaginal ultrasonography to detect tamoxifen-associated endometrial polyps. Ultrasound Obstet Gynecol. 1994 Jan 01;4(1):73-5. doi: 10.1046/j.1469-0705.1994.04010073.x. PMID: 12797230.
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Ultrasound Obstet Gynecol. 1994 Jan 01;4(1):73-5. doi: 10.1046/j.1469-0705.1994.04010073.x.

Use of intracavity saline instillation and transvaginal ultrasonography to detect tamoxifen-associated endometrial polyps.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

T H Bourne, F Lawton, A Leather, S Granberg, S Campbell, W P Collins

Affiliations

  1. Academic Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London, UK.

PMID: 12797230 DOI: 10.1046/j.1469-0705.1994.04010073.x

Abstract

There is sometimes a discrepancy between the apparent thickness of postmenopausal endometria, as determined by transvaginal ultrasonography, and the examination of endometrial biopsies. We describe a case which showed that tamoxifen (20 mg/day over 12 months) decreased impedance to blood flow in the uterine arteries and increased the apparent thickness of the endometrium. Conversely, the analysis of biopsies suggested the presence of an atrophic endometrium. The introduction of sterile saline into the uterine cavity during a repeat ultrasound scan revealed the presence of a large, free-floating endometrial polyp, which was subsequently difficult to see by hysteroscopy.

Copyright 1994 International Society of Ultrasound in Obstetrics and Gynecology

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