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Fernandez H, Bourget P, Lelaidier C, et al. Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations. Ultrasound Obstet Gynecol. 1993;3(5):357-9doi: 10.1046/j.1469-0705.1993.03050357.x.
Fernandez, H., Bourget, P., Lelaidier, C., Doumerc, S., & Frydman, R. (1993). Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 3(5), 357-9. https://doi.org/10.1046/j.1469-0705.1993.03050357.x
Fernandez, H, et al. "Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations." Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology vol. 3,5 (1993): 357-9. doi: https://doi.org/10.1046/j.1469-0705.1993.03050357.x
Fernandez H, Bourget P, Lelaidier C, Doumerc S, Frydman R. Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations. Ultrasound Obstet Gynecol. 1993 Sep 01;3(5):357-9. doi: 10.1046/j.1469-0705.1993.03050357.x. PMID: 12797262.
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Ultrasound Obstet Gynecol. 1993 Sep 01;3(5):357-9. doi: 10.1046/j.1469-0705.1993.03050357.x.

Methotrexate treatment of unilateral twin ectopic pregnancy: case report and pharmacokinetic considerations.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

H Fernandez, P Bourget, C Lelaidier, S Doumerc, R Frydman

Affiliations

  1. Department of Gynecology and Obstetrics, Hôpital Antoine Beclere, Clamart, France.

PMID: 12797262 DOI: 10.1046/j.1469-0705.1993.03050357.x

Abstract

We describe a case of spontaneous twin ectopic pregnancy, managed with the combination of local injection under ultrasound control and intramuscular administration of methotrexate. We describe a difference between the area under the curve of declining plasma concentration of methotrexate after intramuscular and local injection.

Copyright 1993 International Society of Ultrasound in Obstetrics and Gynecology

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