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Ahn MH, Im KI. [Experimental meningoencephalitis by Naegleria fowleri in mice]. Kisaengchunghak Chapchi. 1984;22(2):253-258doi: 10.3347/kjp.1984.22.2.253.
Ahn, M. H., & Im, K. I. (1984). [Experimental meningoencephalitis by Naegleria fowleri in mice]. Kisaengch'unghak chapchi. The Korean journal of parasitology, 22(2), 253-258. https://doi.org/10.3347/kjp.1984.22.2.253
Ahn, Myoung Hee, and Im, Kyung Il. "[Experimental meningoencephalitis by Naegleria fowleri in mice]." Kisaengch'unghak chapchi. The Korean journal of parasitology vol. 22,2 (1984): 253-258. doi: https://doi.org/10.3347/kjp.1984.22.2.253
Ahn MH, Im KI. [Experimental meningoencephalitis by Naegleria fowleri in mice]. Kisaengchunghak Chapchi. 1984 Dec;22(2):253-258. doi: 10.3347/kjp.1984.22.2.253. Korean. PMID: 12891021.
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Kisaengchunghak Chapchi. 1984 Dec;22(2):253-258. doi: 10.3347/kjp.1984.22.2.253.

[Experimental meningoencephalitis by Naegleria fowleri in mice].

Kisaengch'unghak chapchi. The Korean journal of parasitology

[Article in Korean]
Myoung Hee Ahn, Kyung Il Im

Affiliations

  1. Department of Parasitology, College of Medicine, Hanyang University, Korea.

PMID: 12891021 DOI: 10.3347/kjp.1984.22.2.253

Abstract

Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size of N. fowleri trophozoite. In this paper, the effect of these factors on PAM development of mouse was studied. N. fowleri trophozoites, strain 0359, were introduced into mouse intranasally under secobarbital anesthesia (0.05 mg/g). PAM was developed more frequently in BALB/c mouse than ICR mouse. The survival time of mouse with PAM was influenced by the weight, that is, it was shorter in 15 g mouse than in the heavier groups. No difference was observed on PAM development according to sex. In case of inoculated amoeba, PAM incidence of 0.5 x 10(4) was markedly decreased.

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