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Potteiger JA, Carper MJ, Randall JC, et al. Changes in Lower Leg Anterior Compartment Pressure Before, During, and After Creatine Supplementation. J Athl Train. 2002;37(2):157-163
Potteiger, J. A., Carper, M. J., Randall, J. C., Magee, L. J., Jacobsen, D. J., & Hulver, M. W. (2002). Changes in Lower Leg Anterior Compartment Pressure Before, During, and After Creatine Supplementation. Journal of athletic training, 37(2), 157-163.
Potteiger, Jeffrey A, et al. "Changes in Lower Leg Anterior Compartment Pressure Before, During, and After Creatine Supplementation." Journal of athletic training vol. 37,2 (2002): 157-163.
Potteiger JA, Carper MJ, Randall JC, Magee LJ, Jacobsen DJ, Hulver MW. Changes in Lower Leg Anterior Compartment Pressure Before, During, and After Creatine Supplementation. J Athl Train. 2002 Jun;37(2):157-163. PMID: 12937429; PMCID: PMC164339.
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J Athl Train. 2002 Jun;37(2):157-163.

Changes in Lower Leg Anterior Compartment Pressure Before, During, and After Creatine Supplementation.

Journal of athletic training

Jeffrey A Potteiger, Michael J Carper, Jeffrey C Randall, Lawrence J Magee, Dennis J Jacobsen, Mathew W Hulver

Affiliations

  1. University of Kansas, Lawrence, KS.

PMID: 12937429 PMCID: PMC164339

Abstract

OBJECTIVE: To determine if 35 days of creatine supplementation (Cr) followed by 28 days of no supplementation altered lower leg anterior compartment pressure (ACP) at rest and after exercise. DESIGN AND SETTING: Subjects were divided into 2 treatment groups: (1) high dose (0.3 g Cr.kg body mass(-1).d(-1) for 7 days followed by 0.03 g Cr.kg body mass(-1).d(-1) for 28 days), or (2) low dose (0.03 g Cr.kg body mass(-1).d(-1) for 35 days). After 35 days, supplementation was terminated, and no Cr was ingested for 28 days. SUBJECTS: Sixteen physically active, healthy, college-aged males (O(2)max = 47.6 +/- 5.1 mL.kg(-1).min(-1)). MEASUREMENTS: At baseline, 7 days and 35 days of supplementation, and 28 days postsupplementation, ACP was measured preexercise and immediately, 1, 5, 10, and 15 minutes postexercise after a treadmill run at 80% O(2)max. RESULTS: For ACP, there was no significant group-by-time interaction, but there was a significant time effect for group when the data were combined. ACP was significantly increased at preexercise, immediately postexercise, and 1, 5, and 10 minutes from baseline to 7 days. ACP remained significantly elevated from baseline at 35 days immediately postexercise and 1 minute postexercise. After 28 days of no supplementation, ACP began to return to presupplementation levels, with only the 1-minute postexercise measurement significantly elevated from baseline. CONCLUSIONS: Creatine supplementation increased ACP at rest and after exercise, and ACP began to return to normal after 28 days of no supplementation.

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