Display options
Cite
Murray CJ, Ezzati M, Lopez AD, et al. Comparative quantification of health risks conceptual framework and methodological issues. Popul Health Metr. 2003;1(1):1doi: 10.1186/1478-7954-1-1.
Murray, C. J., Ezzati, M., Lopez, A. D., Rodgers, A., & Vander Hoorn, S. (2003). Comparative quantification of health risks conceptual framework and methodological issues. Population health metrics, 1(1), 1. https://doi.org/10.1186/1478-7954-1-1
Murray, Christopher JL, et al. "Comparative quantification of health risks conceptual framework and methodological issues." Population health metrics vol. 1,1 (2003): 1. doi: https://doi.org/10.1186/1478-7954-1-1
Murray CJ, Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S. Comparative quantification of health risks conceptual framework and methodological issues. Popul Health Metr. 2003 Apr 14;1(1):1. doi: 10.1186/1478-7954-1-1. PMID: 12780936; PMCID: PMC156894.
Copy Download .nbib Format: NLM
Share it on

Popul Health Metr. 2003 Apr 14;1(1):1. doi: 10.1186/1478-7954-1-1.

Comparative quantification of health risks conceptual framework and methodological issues.

Population health metrics

Christopher JL Murray, Majid Ezzati, Alan D Lopez, Anthony Rodgers, Stephen Vander Hoorn

Affiliations

  1. Risk, Resources and Environmental Management Division, Resources for the Future, 1616 P Street NW, Washington DC 20036, USA. [email protected]

PMID: 12780936 PMCID: PMC156894 DOI: 10.1186/1478-7954-1-1

Abstract

Reliable and comparable analysis of risks to health is key for preventing disease and injury. Causal attribution of morbidity and mortality to risk factors has traditionally been conducted in the context of methodological traditions of individual risk factors, often in a limited number of settings, restricting comparability.In this paper, we discuss the conceptual and methodological issues for quantifying the population health effects of individual or groups of risk factors in various levels of causality using knowledge from different scientific disciplines. The issues include: comparing the burden of disease due to the observed exposure distribution in a population with the burden from a hypothetical distribution or series of distributions, rather than a single reference level such as non-exposed; considering the multiple stages in the causal network of interactions among risk factor(s) and disease outcome to allow making inferences about some combinations of risk factors for which epidemiological studies have not been conducted, including the joint effects of multiple risk factors; calculating the health loss due to risk factor(s) as a time-indexed "stream" of disease burden due to a time-indexed "stream" of exposure, including consideration of discounting; and the sources of uncertainty.

References

  1. Stat Med. 2000 Dec 15;19(23):3149-64 - PubMed
  2. J Atheroscler Res. 1964 Jul-Aug;4:289-312 - PubMed
  3. JAMA. 2000 Aug 9;284(6):706-12 - PubMed
  4. Lancet. 1995 Dec 23-30;346(8991-8992):1647-53 - PubMed
  5. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13286-93 - PubMed
  6. Am J Med. 1990 Nov;89(5):630-8 - PubMed
  7. J Health Serv Res Policy. 1999 Apr;4(2):112-21 - PubMed
  8. J Clin Epidemiol. 1998 Apr;51(4):305-7 - PubMed
  9. Epidemiology. 1999 Sep;10(5):656-60 - PubMed
  10. Br J Prev Soc Med. 1971 Nov;25(4):242-4 - PubMed
  11. Lancet. 2000 Sep 2;356(9232):795-801 - PubMed
  12. Am J Epidemiol. 1979 Apr;109(4):451-63 - PubMed
  13. Bull World Health Organ. 2000;78(10):1207-21 - PubMed
  14. BMJ. 1994 Feb 5;308(6925):367-72 - PubMed
  15. JAMA. 1993 Nov 10;270(18):2207-12 - PubMed
  16. Am J Epidemiol. 1995 Nov 1;142(9):946-54 - PubMed
  17. Science. 2000 Sep 8;289(5485):1763-6 - PubMed
  18. Acta Unio Int Contra Cancrum. 1953;9(3):531-41 - PubMed
  19. J Epidemiol Community Health. 2000 May;54(5):328-32 - PubMed
  20. Lancet. 1992 May 23;339(8804):1268-78 - PubMed
  21. J Chronic Dis. 1959 Jul;10(1):27-40 - PubMed
  22. Am J Public Health. 1998 Jan;88(1):15-9 - PubMed
  23. J Clin Epidemiol. 1996 Apr;49(4):395-400 - PubMed
  24. Am J Epidemiol. 1993 Dec 1;138(11):973-83 - PubMed
  25. Am J Public Health. 1999 Mar;89(3):385-90 - PubMed
  26. Am J Epidemiol. 1991 Nov 15;134(10):1085-101 - PubMed
  27. IARC Sci Publ. 1986;(74):23-33 - PubMed
  28. Epidemiol Rev. 1987;9:1-30 - PubMed
  29. Biometrics. 1997 Sep;53(3):1170-6 - PubMed
  30. Stat Med. 1984 Apr-Jun;3(2):131-41 - PubMed
  31. Lancet. 1990 Mar 31;335(8692):765-74 - PubMed
  32. Am J Epidemiol. 1974 May;99(5):325-32 - PubMed
  33. Am J Epidemiol. 1988 Dec;128(6):1185-97 - PubMed
  34. Proc R Soc Med. 1965 May;58:295-300 - PubMed
  35. Parasitol Today. 1999 Mar;15(3):105-11 - PubMed
  36. JAMA. 1999 Dec 22-29;282(24):2340-6 - PubMed
  37. Hypertension. 1989 Sep;14(3):238-46 - PubMed
  38. Yale J Biol Med. 1976 May;49(2):175-95 - PubMed
  39. Stat Med. 1991 Jan;10(1):79-93 - PubMed
  40. Med J Aust. 1965 Apr 24;1(17):611-7 - PubMed
  41. J Math Biol. 1986;24(2):119-40 - PubMed
  42. Int J Epidemiol. 2002 Apr;31(2):422-9 - PubMed
  43. Environ Health Perspect. 2000 Sep;108(9):833-9 - PubMed
  44. Epidemiology. 1999 Sep;10(5):594-605 - PubMed
  45. Am J Epidemiol. 1978 Oct;108(4):249-58 - PubMed
  46. Epidemiology. 1991 Mar;2(2):88-97 - PubMed
  47. Addiction. 1999 May;94(5):649-63 - PubMed
  48. Am J Epidemiol. 1976 Dec;104(6):587-92 - PubMed
  49. Stat Methods Med Res. 2001 Jun;10(3):159-93 - PubMed
  50. Thorax. 2000 Jun;55(6):518-32 - PubMed
  51. Am J Epidemiol. 1980 Sep;112(3):409-16 - PubMed
  52. Environ Health Perspect. 2001 Mar;109 Suppl 1:141-61 - PubMed
  53. Epidemiology. 1999 Sep;10(5):626-31 - PubMed
  54. Lancet. 1997 May 17;349(9063):1436-42 - PubMed
  55. Lancet. 1998 Dec 5;352(9143):1801-7 - PubMed
  56. Environ Health Perspect. 2000 Apr;108(4):367-76 - PubMed
  57. Stat Methods Med Res. 2001 Jun;10(3):231-7 - PubMed
  58. Lancet. 2002 Nov 2;360(9343):1347-60 - PubMed
  59. Lancet. 2002 Nov 2;360(9343):1342-3 - PubMed
  60. Epidemiology. 1999 Sep;10(5):573-84 - PubMed
  61. Science. 2002 Apr 26;296(5568):695-8 - PubMed
  62. BMJ. 1991 Aug 3;303(6797):276-82 - PubMed
  63. Addiction. 2000 Oct;95(10):1505-23 - PubMed
  64. Stat Med. 1989 Jul;8(7):845-59 - PubMed
  65. BMJ. 2000 Oct 21;321(7267):983-6 - PubMed

Publication Types

Grant support