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Pesce Delfino V, Lettini T, Vacca E, et al. Biological image analysis for microscopical diagnosis: the work-station S.A.M. (Shape Analytical Morphometry). Pathol Res Pract. 1992;188(4):587-92doi: 10.1016/s0344-0338(11)80061-0.
Pesce Delfino, V., Lettini, T., Vacca, E., Potente, F., Ragone, P., & Ricco, R. (1992). Biological image analysis for microscopical diagnosis: the work-station S.A.M. (Shape Analytical Morphometry). Pathology, research and practice, 188(4), 587-92. https://doi.org/10.1016/s0344-0338(11)80061-0
Pesce Delfino, V, et al. "Biological image analysis for microscopical diagnosis: the work-station S.A.M. (Shape Analytical Morphometry)." Pathology, research and practice vol. 188,4 (1992): 587-92. doi: https://doi.org/10.1016/s0344-0338(11)80061-0
Pesce Delfino V, Lettini T, Vacca E, Potente F, Ragone P, Ricco R. Biological image analysis for microscopical diagnosis: the work-station S.A.M. (Shape Analytical Morphometry). Pathol Res Pract. 1992 Jun;188(4):587-92. doi: 10.1016/s0344-0338(11)80061-0. PMID: 1409094.
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Pathol Res Pract. 1992 Jun;188(4):587-92. doi: 10.1016/s0344-0338(11)80061-0.

Biological image analysis for microscopical diagnosis: the work-station S.A.M. (Shape Analytical Morphometry).

Pathology, research and practice

V Pesce Delfino, T Lettini, E Vacca, F Potente, P Ragone, R Ricco

Affiliations

  1. Research Consortium Digamma, Bari, Italy.

PMID: 1409094 DOI: 10.1016/s0344-0338(11)80061-0

Abstract

The S.A.M. (Shape Analytical Morphometry) software system and its related work-station give a generalized and easy-to-handle tool to face a classic and intriguing problem in biomedical morphological diagnosis. What is the shape of an object in a microscopic image? How can we understand the relationship between size and shape? According to Holloway: "Measurements such as length, width, height, whether in chords or arcs only describe space, ... and further run into the abyss of allometric correction ... if additional information (shape?) to size is expected, some method of allometric correction must be used." The S.A.M. software system assumes a logic architecture able to separate and to parametrize independently shape characteristics in terms of allometry and local pertubation by analytical procedures (polynomials, parabolic fitting, Fourier analysis) in addition to the classic evaluations of size and density carried out by image analyzers for microscopical diagnosis.

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