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Suk WA, Murray K, Avakian MD. Environmental hazards to children's health in the modern world. Mutat Res. 2003;544(2):235-42doi: 10.1016/j.mrrev.2003.06.007.
Suk, W. A., Murray, K., & Avakian, M. D. (2003). Environmental hazards to children's health in the modern world. Mutation research, 544(2), 235-42. https://doi.org/10.1016/j.mrrev.2003.06.007
Suk, William A, et al. "Environmental hazards to children's health in the modern world." Mutation research vol. 544,2 (2003): 235-42. doi: https://doi.org/10.1016/j.mrrev.2003.06.007
Suk WA, Murray K, Avakian MD. Environmental hazards to children's health in the modern world. Mutat Res. 2003 Nov;544(2):235-42. doi: 10.1016/j.mrrev.2003.06.007. PMID: 14644325.
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Mutat Res. 2003 Nov;544(2):235-42. doi: 10.1016/j.mrrev.2003.06.007.

Environmental hazards to children's health in the modern world.

Mutation research

William A Suk, Kerry Murray, Maureen D Avakian

Affiliations

  1. Center for Risk and Integrated Sciences, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, NC 27709, USA. [email protected]

PMID: 14644325 DOI: 10.1016/j.mrrev.2003.06.007

Abstract

Patterns of illness in children have changed dramatically in the last century, and will continue to change in this century. The major diseases confronting children are now chronic and disabling conditions termed the "new pediatric morbidity"-asthma, leukemia and brain cancer, neurodevelopmental dysfunction and neurobehavioral abnormality, reproductive and systemic developmental problems. Chemical toxicants in the environment, poverty, and little or no access to health care are all factors contributing to life-threatening pediatric diseases; children are uniquely vulnerable to chemical toxicants because of their disproportionately heavy exposures and their inherent biological growth and development. Genetic susceptibility and environmental exposures during vulnerable periods of development are also important contributors to the etiologies of many diseases of childhood. It is vital that we develop a better understanding of the mechanisms and interactions between nutrition, infectious disease, environmental exposures, and genetic predisposition in order to develop better prevention methods. This paper briefly examines modern contributors to children's environmental health problems, efforts to date on both the regional and international level to address these challenges, and reflects upon major research needs that must be addressed in order to close the gaps that exist in our understanding of the relationship between environmental exposures and children's health.

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