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Ann Gen Hosp Psychiatry. 2003 Oct 17;2(1):9. doi: 10.1186/1475-2832-2-9.

Treatment of severe neuroleptic-induced tardive torticollis.

Annals of general hospital psychiatry

Beata J Havaki-Kontaxaki, Vassilis P Kontaxakis, Maria M Margariti, Konstantinos G Paplos, George N Christodoulou

Affiliations

  1. Department of Psychiatry, University of Athens, Eginition Hospital, Athens, Greece. [email protected]

PMID: 14613515 PMCID: PMC270069 DOI: 10.1186/1475-2832-2-9

Abstract

BACKGROUND: The aim of this paper is to describe a case of severe neuroleptic-induced tardive torticollis successfully treated with a combination of clozapine, clonazepam and botulinum toxin-A. CASE REPORT: The patient, a 30-year old man with a seven-year history of delusional disorder experienced severe right torticollis with painful tightness of the neck and elevation of the shoulder. At this time he was receiving haloperidol 20 mg, trifluoperazine 5 mg, zuclopenthixol 20 mg and biperidine 4 mg daily. The combination therapy with clozapine and clonazepam and the long-term use of botulinum toxin-A resulted in a complete remission of dystonic movements. CONCLUSIONS: The present observations provide evidence indicating that this combination therapy may be of benefit in patients with severe neuroleptic-induced tardive torticollis.

References

  1. J Clin Psychopharmacol. 1997 Dec;17(6):497-8 - PubMed
  2. Biol Psychiatry. 1999 Mar 15;45(6):715-30 - PubMed
  3. J Clin Psychopharmacol. 1990 Dec;10(6):438-9 - PubMed
  4. Am J Psychiatry. 1979 Mar;136(3):317-20 - PubMed
  5. Brain. 1998 Nov;121 ( Pt 11):2053-66 - PubMed
  6. J Neuropsychiatry Clin Neurosci. 2002 Summer;14 (3):355-6 - PubMed
  7. J Nerv Ment Dis. 1993 Feb;181(2):137-8 - PubMed
  8. J Clin Psychopharmacol. 1991 Aug;11(4):268-9 - PubMed
  9. Clin Neuropharmacol. 1997 Feb;20(1):90-3 - PubMed
  10. Neurology. 1982 Dec;32(12):1335-46 - PubMed
  11. Lancet. 1986 Aug 2;2(8501):245-7 - PubMed
  12. J Neuropsychiatry Clin Neurosci. 1994 Winter;6(1):50-3 - PubMed
  13. Biol Psychiatry. 1996 Jun 15;39(12):1064-5 - PubMed
  14. Schizophr Bull. 1999;25(4):741-8 - PubMed
  15. Mov Disord. 1994 May;9(3):321-4 - PubMed
  16. Prog Neuropsychopharmacol Biol Psychiatry. 1996 Feb;20(2):263-74 - PubMed
  17. Am J Psychiatry. 1999 Dec;156(12 ):2016 - PubMed
  18. Br J Psychiatry. 1996 Apr;168(4):516-8 - PubMed
  19. Br J Psychiatry. 1991 Apr;158:503-10 - PubMed
  20. Mov Disord. 1994 Jul;9(4):441-6 - PubMed
  21. Arch Gen Psychiatry. 1998 Mar;55(3):279-80 - PubMed

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