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Trends Cell Biol. 1993 Nov;3(11):409-12. doi: 10.1016/0962-8924(93)90092-f.

The control of ciliary beat frequency.

Trends in cell biology

P Satir, K Barkalow, T Hamasaki

Affiliations

  1. Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

PMID: 14731660 DOI: 10.1016/0962-8924(93)90092-f

Abstract

Ciliary movement is powered by axonemal dynein. This article considers how a signal transduction cascade initiated at the cell membrane may activate outer dynein arms to change the velocity of microtubule sliding and the swimming speed of ciliated cells. For Paramecium, a critical event in the cascade is the cAMP-dependent phosphorylation of a 29 kDa polypeptide that is associated with the outer dynein arm.

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