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Grindem CB, Stevens JB, Perman V. Chemical reactions in cells from leukemic cats. Vet Clin Pathol. 1985;14(3):6-12doi: 10.1111/j.1939-165x.1985.tb00855.x.
Grindem, C. B., Stevens, J. B., & Perman, V. (1985). Chemical reactions in cells from leukemic cats. Veterinary clinical pathology, 14(3), 6-12. https://doi.org/10.1111/j.1939-165x.1985.tb00855.x
Grindem, C B, et al. "Chemical reactions in cells from leukemic cats." Veterinary clinical pathology vol. 14,3 (1985): 6-12. doi: https://doi.org/10.1111/j.1939-165x.1985.tb00855.x
Grindem CB, Stevens JB, Perman V. Chemical reactions in cells from leukemic cats. Vet Clin Pathol. 1985;14(3):6-12. doi: 10.1111/j.1939-165x.1985.tb00855.x. PMID: 15221680.
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Vet Clin Pathol. 1985;14(3):6-12. doi: 10.1111/j.1939-165x.1985.tb00855.x.

Chemical reactions in cells from leukemic cats.

Veterinary clinical pathology

C B Grindem, J B Stevens, V Perman

Affiliations

  1. Department of Veterinary Microbiology, Parasitology, and Pathology North Carolina State University, Raleigh, North Carolina 27606.

PMID: 15221680 DOI: 10.1111/j.1939-165x.1985.tb00855.x

Abstract

Cytochemical staining for leukocyte alkaline phosphatase(LAP), nonspecific esterase (NSE), nonspecific esterase with fluoride inhibition (NSE-F), periodic acid Schiff (PAS) reactivity, and peroxidase (PO) was valuable in identification of the neoplastic cell type in 10 leukemic cats. Staining both blood and bone marrow smears was often necessary for making the correct diagnosis. Cytochemical staining resulted in changing the morphologic diagnosis of leukemia in two of the 10 cats. Also, increased LAP activity, probably a marker for myelocytic leukemia in the cat, was observed in bone marrow cells from three nonleukemic, FeLV-positive cats.

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