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Tex Heart Inst J. 1991;18(3):186-93.

Mediastinitis and mycotic aneurysm of the aorta after orthotopic heart transplantation.

Texas Heart Institute journal

M Anthuber, B M Kemkes, E Kreuzer, M Gokel, A Schuetz, C Kugler, F Sudhoff

Affiliations

  1. Department of Cardiac Surgery, University Hospital Munich Grosshadern, Munich, Federal Republic of Germany.

PMID: 15227478 PMCID: PMC324995

Abstract

After cardiac transplantation, bacterial mediastinitis is a rare but dangerous early complication. Of the 113 patients who underwent heart or heart-lung transplantation at our hospital from August 1981 to April 1989, 8 developed purulent mediastinitis. Treatment involved surgical débridment, local irrigation, drainage, and high-dose systemic antibiotics. No patient died of an acute mediastinal infection. In 2 cases, however, chronic mediastinitis led to the formation of a huge mycotic aneurysm of the ascending aorta. Eleven days after surgical intervention for rupture, 1 patient died of aneurysmal rerupture; the 2nd patient remains well 16 months after prosthetic replacement of the ascending aorta and reconstruction of the necrotic proximal portion of the left coronary artery with a saphenous vein patch.

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