Display options
Cite
Kino R, Daikai K, Kawanami T, et al. Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones. Org Biomol Chem. 2004;2(13):1822-4doi: 10.1039/b405882h.
Kino, R., Daikai, K., Kawanami, T., Furuno, H., & Inanaga, J. (2004). Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones. Organic & biomolecular chemistry, 2(13), 1822-4. https://doi.org/10.1039/b405882h
Kino, Rie, et al. "Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones." Organic & biomolecular chemistry vol. 2,13 (2004): 1822-4. doi: https://doi.org/10.1039/b405882h
Kino R, Daikai K, Kawanami T, Furuno H, Inanaga J. Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones. Org Biomol Chem. 2004 Jul 07;2(13):1822-4. doi: 10.1039/b405882h. Epub 2004 Jun 04. PMID: 15227531.
Copy Download .nbib Format: NLM
Share it on

Org Biomol Chem. 2004 Jul 07;2(13):1822-4. doi: 10.1039/b405882h. Epub 2004 Jun 04.

Remarkable effect of tris(4-fluorophenyl)phosphine oxide on the stabilization of chiral lanthanum complex catalysts. A new and practical protocol for the highly enantioselective epoxidation of conjugated enones.

Organic & biomolecular chemistry

Rie Kino, Kazuhiro Daikai, Toshio Kawanami, Hiroshi Furuno, Junji Inanaga

Affiliations

  1. Institute for Materials Chemistry and Engineering, Kyushu University, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.

PMID: 15227531 DOI: 10.1039/b405882h

Abstract

A new and efficient chiral catalyst system, lanthanum-chiral BINOL-tris(4-fluorophenyl)phosphine oxide-cumene hydroperoxide, was developed for the epoxidation of alpha, beta-unsaturated ketones thus providing the corresponding epoxy ketones with excellent enantioselectivities (up to >99% ee) in good to excellent yields at room temperature.

Publication Types