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Bauer JE, Verlander JW. Congenital lipoprotein lipase deficiency in hyperlipemic kitten siblings. Vet Clin Pathol. 1984;13(2):7-11doi: 10.1111/j.1939-165X.1984.tb00626.x.
Bauer, J. E., & Verlander, J. W. (1984). Congenital lipoprotein lipase deficiency in hyperlipemic kitten siblings. Veterinary clinical pathology, 13(2), 7-11. https://doi.org/10.1111/j.1939-165X.1984.tb00626.x
Bauer, J E, and Verlander, J W. "Congenital lipoprotein lipase deficiency in hyperlipemic kitten siblings." Veterinary clinical pathology vol. 13,2 (1984): 7-11. doi: https://doi.org/10.1111/j.1939-165X.1984.tb00626.x
Bauer JE, Verlander JW. Congenital lipoprotein lipase deficiency in hyperlipemic kitten siblings. Vet Clin Pathol. 1984 Apr;13(2):7-11. doi: 10.1111/j.1939-165X.1984.tb00626.x. PMID: 15311389.
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Vet Clin Pathol. 1984 Apr;13(2):7-11. doi: 10.1111/j.1939-165X.1984.tb00626.x.

Congenital lipoprotein lipase deficiency in hyperlipemic kitten siblings.

Veterinary clinical pathology

J E Bauer, J W Verlander

Affiliations

  1. Department of Physiological SciencesDepartment of Medical Sciences College of Veterinary Medicine University of Florida Gainesville, Florida32610.

PMID: 15311389 DOI: 10.1111/j.1939-165X.1984.tb00626.x

Abstract

The nature of the hyperlipemia in two 3-week-old male kittens, one of which was presented with the owner's complaints of retarded growth and white streaks on its eyes, was studied. Hypertriglyceridemia, hyper-cholesterolemia, and reduced Post-Heparin Plasma Lipolytic Activities (PHPLA) were observed in both animals. One of the kittens, however, was more severely affected and in addition, had lipemia retinalis and a marked lactescent, hyperchylomicronemic serum in spite of a short-term fast before sampling. These findings are strikingly similar to those found in human Type I hyperlipoproteinemia due to familial Lipoprotein Lipase (LPL) deficiency. Diagnosis of persistent hyperlipemic syndromes in kittens should include the possibility of LPL deficiency as determined by PHPLA measurements.

© 1984 American Society for Veterinary Pathology.

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