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J Mater Sci Mater Med. 2002 Jan;13(1):107-11. doi: 10.1023/a:1013659208319.

Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate.

Journal of materials science. Materials in medicine

Martin Prádný, Pavel Petrovický, Václava Fronková, Jirí Vacík, Karel Smetana

Affiliations

  1. Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06 Prague 6, Czech Republic. [email protected]

PMID: 15348214 DOI: 10.1023/a:1013659208319

Abstract

This study compares subcutaneous and intracerebral biocompatibilty of two hydrogels: copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate and poly(2-hydroxyethyl methacrylate) as reference polymer. The experimental copolymer was more biologically inert than poly(2-hydroxyethyl methacrylate) in both the studied parameters, hence the former material is a suitable candidate for biomedical application.

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