Display options
Cite
Novello WP, Arruda AC, Santana MH, et al. Characterization of coatings for open-heart surgery tubing with heparin and lipid. J Mater Sci Mater Med. 1998;9(12):793-6doi: 10.1023/a:1008931825245.
Novello, W. P., Arruda, A. C., Santana, M. H., Moraes, A. M., & Pinho, S. C. (1998). Characterization of coatings for open-heart surgery tubing with heparin and lipid. Journal of materials science. Materials in medicine, 9(12), 793-6. https://doi.org/10.1023/a:1008931825245
Novello, W P, et al. "Characterization of coatings for open-heart surgery tubing with heparin and lipid." Journal of materials science. Materials in medicine vol. 9,12 (1998): 793-6. doi: https://doi.org/10.1023/a:1008931825245
Novello WP, Arruda AC, Santana MH, Moraes AM, Pinho SC. Characterization of coatings for open-heart surgery tubing with heparin and lipid. J Mater Sci Mater Med. 1998 Dec;9(12):793-6. doi: 10.1023/a:1008931825245. PMID: 15348942.
Copy Download .nbib Format: NLM
Share it on

J Mater Sci Mater Med. 1998 Dec;9(12):793-6. doi: 10.1023/a:1008931825245.

Characterization of coatings for open-heart surgery tubing with heparin and lipid.

Journal of materials science. Materials in medicine

W P Novello, A C Arruda, M H Santana, A M Moraes, S C Pinho

Affiliations

  1. Biomechanical Engineering Laboratory, University of Campinas, Cidade Universitária Zeferino Vaz, Brazil. [email protected]

PMID: 15348942 DOI: 10.1023/a:1008931825245

Abstract

The aim of this study was to compare qualitative and quantitative methods for coating characterization on internal surfaces of polyvinyl chloride (PVC) tubing used in procedures of extracorporeal circulation. The methods of characterization included optical microscopy (OM) after dyeing with toluidine blue, scanning electron microscopy (SEM), atomic force microscopy (AFM) and energy dispersive spectrometry (EDS). OM after sample dyeing was excellent in allowing early detection of any absence or irregularities of coatings among the used methods. SEM was the most effective in observing the structure and thickness either in heparin coatings or in lipid coatings. AFM provided a good evaluation of the surface topography. A conjunction of all methods is recommended for complete characterization. The quantification methods based on colorimetric tests were efficient in determining the concentrations of heparin and lipid on internal surface tubes, the coating stability and the reproducibility of the results.

Copyright 1998 Kluwer Academic Publishers

References

  1. J Biomater Sci Polym Ed. 1994;6(1):1-13 - PubMed
  2. J Biomater Sci Polym Ed. 1994;6(2):181-93 - PubMed
  3. Ann N Y Acad Sci. 1987;516:116-30 - PubMed
  4. Thromb Res. 1980 Jul 1-15;19(1-2):43-54 - PubMed
  5. Ann N Y Acad Sci. 1987;516:102-15 - PubMed
  6. Artif Organs. 1991 Dec;15(6):481-91 - PubMed
  7. Anal Biochem. 1976 May 7;72:248-54 - PubMed
  8. J Biomater Sci Polym Ed. 1994;6(8):707-14 - PubMed

Publication Types