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Simpson AJ. Schistosome surface antigens: developmental expression and immunological function. Parasitol Today. 1990;6(2):40-5doi: 10.1016/0169-4758(90)90067-e.
Simpson, A. J. (1990). Schistosome surface antigens: developmental expression and immunological function. Parasitology today (Personal ed.), 6(2), 40-5. https://doi.org/10.1016/0169-4758(90)90067-e
Simpson, A J. "Schistosome surface antigens: developmental expression and immunological function." Parasitology today (Personal ed.) vol. 6,2 (1990): 40-5. doi: https://doi.org/10.1016/0169-4758(90)90067-e
Simpson AJ. Schistosome surface antigens: developmental expression and immunological function. Parasitol Today. 1990 Feb;6(2):40-5. doi: 10.1016/0169-4758(90)90067-e. PMID: 15463291.
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Parasitol Today. 1990 Feb;6(2):40-5. doi: 10.1016/0169-4758(90)90067-e.

Schistosome surface antigens: developmental expression and immunological function.

Parasitology today (Personal ed.)

A J Simpson

Affiliations

  1. Division of Parasitology, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

PMID: 15463291 DOI: 10.1016/0169-4758(90)90067-e

Abstract

It has long been held as axiomatic that antigens exposed on the surfaces of parasitic organisms are primary targets of protective immune responses. It is becoming apparent that not all protective schistosome antigens are surface antigens and that not all surface antigens are necessarily targets of protective immunity. Andy Simpson suggests that one of the factors that determines the immunological function of surface antigens may be developmental expression.

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