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J Obstet Gynaecol. 1997 Jun;17(4):340-3. doi: 10.1080/01443619750112754.

Serum concentrations of iodine, thyroxine (T4), triiodothyronine (T3), thyrotropin (TSH) and insulin-like growth factor 1 (IGF-1) during the last trimester of pregnancy, during labour, and in early puerperium of women with normal pregnancy or with intrauterine growth retardation (IUGR).

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

G Peiker, R Glöckner, W Michels, G Hauck, C Malsch, A Börner

Affiliations

  1. Department of Obstetrics and Gynaecology, Freidrich-Schiller-University, Jena, Germany.

PMID: 15511878 DOI: 10.1080/01443619750112754

Abstract

In women with intrauterine growth retardation (IUGR), insulin-like growth factor 1 (IGF-1) concentrations tended to reduce during the last trimester of pregnancy. Parameters of thyroid function in maternal serum were not distinctly influenced by IUGR, except for high concentrations of iodine. Triiodothyronine (T3) concentrations in cord blood of normal pregnancies was significantly lower than maternal concentrations, but was relatively high when the fetus was growth retarded. The results are discussed in connection with changes of thyroid function and changes of IGF-1 during pregnancy.

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