Display options
Cite
Murphy JA, Commeureuc AG, Snaddon TN, et al. Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction. Org Lett. 2005;7(7):1427-9doi: 10.1021/ol050337b.
Murphy, J. A., Commeureuc, A. G., Snaddon, T. N., McGuire, T. M., Khan, T. A., Hisler, K., Dewis, M. L., & Carling, R. (2005). Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction. Organic letters, 7(7), 1427-9. https://doi.org/10.1021/ol050337b
Murphy, John A, et al. "Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction." Organic letters vol. 7,7 (2005): 1427-9. doi: https://doi.org/10.1021/ol050337b
Murphy JA, Commeureuc AG, Snaddon TN, McGuire TM, Khan TA, Hisler K, Dewis ML, Carling R. Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction. Org Lett. 2005 Mar 31;7(7):1427-9. doi: 10.1021/ol050337b. PMID: 15787523.
Copy Download .nbib Format: NLM
Share it on

Org Lett. 2005 Mar 31;7(7):1427-9. doi: 10.1021/ol050337b.

Direct conversion of N-methoxy-N-methylamides (Weinreb amides) to ketones via a nonclassical Wittig reaction.

Organic letters

John A Murphy, Aurélien G J Commeureuc, Thomas N Snaddon, Thomas M McGuire, Tanweer A Khan, Kevin Hisler, Mark L Dewis, Robert Carling

Affiliations

  1. Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, UK. [email protected]

PMID: 15787523 DOI: 10.1021/ol050337b

Abstract

[reaction: see text] N-Methoxy-N-methylamides (Weinreb amides) are converted efficiently into ketones by reaction with alkylidenetriphenylphosphoranes and in situ hydrolysis of the product.

Publication Types