Display options
Share it on

Skull Base. 2003 Feb;13(1):13-19. doi: 10.1055/s-2003-820553.

Clinical and Histologic Parameters Correlated with Facial Nerve Function After Vestibular Schwannoma Surgery.

Skull base : official journal of North American Skull Base Society ... [et al.]

Vincent Couloigner, Elena Gervaz, Michel Kalamarides, Evelyne Ferrary, Alain Rey, Olivier Sterkers, Dominique Hénin

Affiliations

  1. Department of Oto–Rhino–Laryngology, Hôpital Beaujon, AP–HP, Clichy, France.

PMID: 15912155 PMCID: PMC1131825 DOI: 10.1055/s-2003-820553

Abstract

This study was conducted to identify clinical and histologic factors that would influence, independently of tumor staging, postoperative facial function after removal of a vestibular schwannoma. A prospective study was performed on 35 consecutive patients with vestibular schwannomas who underwent the translabyrinthine approach. Facial function was assessed before and 1 year after surgery. The factors that influenced the postoperative outcome of the facial function independently of tumor staging were the absence or the desynchronization of homolateral auditory brainstem responses and tumor edema. Other factors (audiovestibular signs of brainstem compression, tumor inflammation, positive p53 protein immunostaining) were predictive of postoperative facial function but also correlated with tumor staging. Besides the well-known prognostic value of tumor staging for postoperative facial outcome, clinical (auditory brainstem responses) and histologic (tumor edema) factors correlated with postoperative facial function.

References

  1. Acta Otolaryngol. 2000 Oct;120(8):950-4 - PubMed
  2. Acta Otolaryngol Suppl. 1998;537:11-5 - PubMed
  3. J Histochem Cytochem. 1966 Apr;14(4):291-302 - PubMed
  4. Pathol Res Pract. 1994 Dec;190(12):1141-8 - PubMed
  5. Neurosurgery. 1979 May;4(5):418-21 - PubMed
  6. Clin Otolaryngol Allied Sci. 1996 Oct;21(5):409-13 - PubMed
  7. Otolaryngol Clin North Am. 1992 Jun;25(3):623-47 - PubMed
  8. Neurosurgery. 1997 Apr;40(4):684-94; discussion 694-5 - PubMed
  9. J Cell Biol. 1974 Feb;60(2):523-7 - PubMed
  10. Acta Otolaryngol. 1996 Jan;116(1):59-63 - PubMed
  11. Otolaryngol Head Neck Surg. 1994 Feb;110(2):146-55 - PubMed
  12. J Histochem Cytochem. 1979 Apr;27(4):832-40 - PubMed
  13. Otol Neurotol. 2001 Jan;22(1):79-86 - PubMed
  14. Otolaryngol Head Neck Surg. 1985 Apr;93(2):146-7 - PubMed
  15. Arch Otolaryngol. 1968 Dec;88(6):586-91 - PubMed
  16. Clin Otolaryngol Allied Sci. 1999 Dec;24(6):483-6 - PubMed
  17. Laryngoscope. 1996 Jan;106(1 Pt 1):58-66 - PubMed
  18. J Neurosurg. 1997 Jul;87(1):60-6 - PubMed
  19. J Laryngol Otol. 1998 May;112(5):441-5 - PubMed

Publication Types