Clin Calcium. 2001 Jan;11(1):87-91. doi: CliCa01018791.
Clinical calcium
[Article in Japanese] T Matsumoto
PMID: 15775498 DOI: CliCa01018791
In order to prevent osteoporotic fractures, various drugs with anti-resorptive effects have been developed. These include new generation of bisphosphonates and selective estrogen receptor modulators. There are also agents under development with stimulatory effect on bone formation, including parathyroid hormone, new active vitamin D analogs and statins. Examination of clinical efficacy of these agents either alone or in combination for preventing fractures should help establishing better treatment for osteoporosis.