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J Low Genit Tract Dis. 2004 Jan;8(1):38-42. doi: 10.1097/00128360-200401000-00009.

Primary adenocarcinoma of the vagina with mucinous-enteric differentiation: a report of two cases with associated vaginal adenosis without history of diethylstilbestrol exposure.

Journal of lower genital tract disease

Dietrich Werner, Edward J Wilkinson, Daylene Ripley, Anthony Yachnis

Affiliations

  1. Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.

PMID: 15874835 DOI: 10.1097/00128360-200401000-00009

Abstract

Primary adenocarcinoma of the vagina is rare, and mucinous-enteric differentiation is exceptional. A few sporadic cases of primary vaginal adenocarcinoma with mucinous-enteric differentiation have been reported. Reports of the clinical histories, pathologic findings, and immunohistochemical studies of two cases of primary vaginal adenocarcinomas in a 67-year-old and in a 45-year-old woman are presented. Knowledge of the differentiation of Mullerian epithelium and immunohistochemistry studies are helpful to better characterize these tumors.

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