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Tam T, Li W, Leung-Toung R, et al. Recent advances in proton pump inhibitors. IDrugs. 2000;3(9):1064-74
Tam, T., Li, W., Leung-Toung, R., & Karimian, K. (2000). Recent advances in proton pump inhibitors. IDrugs : the investigational drugs journal, 3(9), 1064-74.
Tam, T, et al. "Recent advances in proton pump inhibitors." IDrugs : the investigational drugs journal vol. 3,9 (2000): 1064-74.
Tam T, Li W, Leung-Toung R, Karimian K. Recent advances in proton pump inhibitors. IDrugs. 2000 Sep;3(9):1064-74. PMID: 16049866.
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IDrugs. 2000 Sep;3(9):1064-74.

Recent advances in proton pump inhibitors.

IDrugs : the investigational drugs journal

T Tam, W Li, R Leung-Toung, K Karimian

Affiliations

  1. Apotex Research Inc, Medicinal Chemistry Department, 150 Signet Drive, Toronto, Ontario M9L 1T9, Canada.

PMID: 16049866

Abstract

Mechanism of action and shortcomings of the approved proton pump inhibitors are reviewed. Advances in the design of new proton pump K(+) and S site inhibitors are presented. Design criteria incorporated into the structure of investigational proton pump inhibitors to address these drawbacks are discussed.

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