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Khokhar AS, Seidner DL. The pathophysiology of pancreatitis. Nutr Clin Pract. 2004;19(1):5-15doi: 10.1177/011542650401900105.
Khokhar, A. S., & Seidner, D. L. (2004). The pathophysiology of pancreatitis. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 19(1), 5-15. https://doi.org/10.1177/011542650401900105
Khokhar, Asim S, and Seidner, Douglas L. "The pathophysiology of pancreatitis." Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition vol. 19,1 (2004): 5-15. doi: https://doi.org/10.1177/011542650401900105
Khokhar AS, Seidner DL. The pathophysiology of pancreatitis. Nutr Clin Pract. 2004 Feb;19(1):5-15. doi: 10.1177/011542650401900105. PMID: 16215091.
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Nutr Clin Pract. 2004 Feb;19(1):5-15. doi: 10.1177/011542650401900105.

The pathophysiology of pancreatitis.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

Asim S Khokhar, Douglas L Seidner

Affiliations

  1. Nutrition Support and Vascular Access Team, Department of Gastroenterology and Hepatology/A-30, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

PMID: 16215091 DOI: 10.1177/011542650401900105

Abstract

The pancreas is an exocrine and endocrine gland that is required for normal digestion and metabolism of proteins, carbohydrates, and fats. Acute pancreatitis (AP) is an inflammatory process of the pancreas that involves peripancreatic tissues and remote organs. Mild AP occurs in 80% of patients requiring hospitalization and severe AP occurs in the other 20%. Chronic pancreatitis (CP) is an inflammatory disorder that causes anatomic changes, including infiltration of chronic inflammatory cells and fibrosis of the pancreas. This review discusses biochemical and histologic features of pancreatic injury in AP and CP and some of the important clinical sequelae associated with these abnormalities.

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