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N Z Vet J. 1996 Apr;44(2):64-6. doi: 10.1080/00480169.1996.35936.

The efficacy of a Leptospira interrogans serovars pomona and copenhageni and L. borgpetersenii serovar hardjo vaccine in cattle.

New Zealand veterinary journal

A Palit, A M Alexander, B Slacek, C Taylor

Affiliations

  1. CSL Limited, 45 Poplar Road, Parkville, Victoria 3052, Australia.

PMID: 16031896 DOI: 10.1080/00480169.1996.35936

Abstract

An experimental, trivalent, bovine, leptospiral vaccine, containing inactivated Leptospira interrogans serovars pomona and copenhageni and L. borgpetersenii serovar hardjo Hardjobovis, was developed. The experimental vaccine was shown to protect hamsters against virulent challenge with each of the component serovars. In a serological efficacy test in cattle, the experimental vaccine was compared for bioequivalence with a similar product, registered in New Zealand for veterinary use. The experimental vaccine induced higher titres in cattle than the latter mentioned product.

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