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Int Semin Surg Oncol. 2005 Aug 30;2:16. doi: 10.1186/1477-7800-2-16.

Our local experience with the surgical treatment of ampullary cancer.

International seminars in surgical oncology : ISSO

Dimitrios Botsios, Emmanouil Zacharakis, Ioannis Lambrou, Kostas Tsalis, Emmanouil Christoforidis, Stavros Kalfadis, Evangelos Zacharakis, Dimitrios Betsis, Ioannis Dadoukis

Affiliations

  1. 4th Surgical Department, Aristotle University of Thessaloniki, G, Papanikolaou General Regional Hospital, Exohi, Thessaloniki 57010, Greece. [email protected]

PMID: 16131399 PMCID: PMC1215507 DOI: 10.1186/1477-7800-2-16

Abstract

BACKGROUND: The aim of this study is to report the outcome after surgical treatment of 32 patients with ampullary cancers from 1990 to 1999.

METHODS: Twenty-one of them underwent pancreaticoduodenectomy and 9 local excision of the ampullary lesion. The remaining 2 patients underwent palliative surgery.

RESULTS: When the final histological diagnosis was compared with the preoperative histological finding on biopsy, accurate diagnosis was preoperatively established in 24 patients. The hospital morbidity was 18.8% as 9 complications occurred in 6 patients. Following local excision of the ampullary cancer, the survival rate at 3 and 5 years was 77.7% and 33.3% respectively. Among the patients that underwent Whipple's procedure, the 3-year survival rate was 76.2% and the 5-year survival rate 62%.

CONCLUSION: In this series, local resection was a safe option in patients with significant co-morbidity or small ampullary tumors less than 2 cm in size, and was associated with satisfactory long-term survival rates.

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