Display options
Cite
Craig MI, Barrandeguy ME, Fernández FM. Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina. BMC Vet Res. 2005;1:9doi: 10.1186/1746-6148-1-9.
Craig, M. I., Barrandeguy, M. E., & Fernández, F. M. (2005). Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina. BMC veterinary research, 19. https://doi.org/10.1186/1746-6148-1-9
Craig, María I, et al. "Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina." BMC veterinary research vol. 1 (2005): 9. doi: https://doi.org/10.1186/1746-6148-1-9
Craig MI, Barrandeguy ME, Fernández FM. Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina. BMC Vet Res. 2005 Nov 09;1:9. doi: 10.1186/1746-6148-1-9. PMID: 16281971; PMCID: PMC1308826.
Copy Download .nbib Format: NLM
Share it on

BMC Vet Res. 2005 Nov 09;1:9. doi: 10.1186/1746-6148-1-9.

Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina.

BMC veterinary research

María I Craig, María E Barrandeguy, Fernando M Fernández

Affiliations

  1. Instituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas (CICVyA), INTA, CC 25, (1712) Castelar, Buenos Aires, Argentina. [email protected]

PMID: 16281971 PMCID: PMC1308826 DOI: 10.1186/1746-6148-1-9

Abstract

BACKGROUND: Equine herpesvirus 2 is a gamma-herpesvirus that infects horses worldwide. Although EHV-2 has been implicated in immunosuppression in foals, upper respiratory tract disease, conjunctivitis, general malaise and poor performance, its precise role as a pathogen remains uncertain. The purpose of the present study was to analyse the incidence of EHV-2 in an Argentinean horse population and correlate it with age and clinical status of the animals.

RESULTS: A serological study on 153 thoroughbred racing horses confirmed the presence of EHV-2 in the Argentinean equine population. A virus neutralization test showed a total of 79.7 % animals were sero-positive for EHV-2. An increase in antibodies titre with age as well as infection at earlier ages were observed.EHV-2 was isolated from 2 out of 22 nasal swabs from horses showing respiratory symptoms. The virus grew slowly and showed characteristic cytopathic effect after several blind passages on RK13 cells. The identity of the isolates was confirmed by nested PCR and restriction enzyme assay (REA).

CONCLUSION: This is the first report on the presence of EHV-2 in Argentina and adds new data to the virus distribution map. Though EHV-2 was isolated from foals showing respiratory symptoms, further studies are needed to unequivocally associate this virus with clinical symptoms.

References

  1. Arch Virol. 1989;104(1-2):77-86 - PubMed
  2. Can J Microbiol. 1975 Dec;21(12):1940-6 - PubMed
  3. Zentralbl Veterinarmed B. 1978 Mar;25(2):165-7 - PubMed
  4. Aust Vet J. 1972 Feb;48(2):47-53 - PubMed
  5. Aust Vet J. 1974 Nov;50(11):483-8 - PubMed
  6. Aust Vet J. 1970 Mar;46(3):83-9 - PubMed
  7. Am J Vet Res. 1974 Sep;35(9):1169-72 - PubMed
  8. Infect Immun. 1973 Oct;8(4):621-7 - PubMed
  9. Vet Rec. 1975 May 3;96(18):404-5 - PubMed
  10. Virology. 1963 Mar;19:412-6 - PubMed
  11. Ann Inst Pasteur (Paris). 1966 May;110(5):688-96 - PubMed
  12. Can J Comp Med. 1970 Jan;34(1):59-65 - PubMed
  13. Zentralbl Veterinarmed B. 1980;27(9-10):826-30 - PubMed
  14. J Vet Diagn Invest. 2001 Sep;13(5):389-93 - PubMed
  15. J Clin Microbiol. 1977 Mar;5(3):285-9 - PubMed
  16. J Am Vet Med Assoc. 1994 Jul 15;205(2):329-31 - PubMed
  17. Acta Virol. 2004;48(3):189-92 - PubMed
  18. Am J Vet Res. 1974 Feb;35(2):181-5 - PubMed
  19. Adv Virus Res. 1994;44:357-79 - PubMed
  20. Arch Virol. 1997;142(5):917-28 - PubMed
  21. Cornell Vet. 1974 Jan;64(1):94-122 - PubMed
  22. N Z Vet J. 1976 Aug;24(8):171-6 - PubMed
  23. Arch Exp Veterinarmed. 1967;21:115-9 - PubMed

Publication Types