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Riov J, Jaffe MJ. Cholinesterases from Plant Tissues: II. Inhibition of Bean Cholinesterase by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride (AMO-1618). Plant Physiol. 1973;52(3):233-5doi: 10.1104/pp.52.3.233.
Riov, J., & Jaffe, M. J. (1973). Cholinesterases from Plant Tissues: II. Inhibition of Bean Cholinesterase by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride (AMO-1618). Plant physiology, 52(3), 233-5. https://doi.org/10.1104/pp.52.3.233
Riov, J, and Jaffe, M J. "Cholinesterases from Plant Tissues: II. Inhibition of Bean Cholinesterase by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride (AMO-1618)." Plant physiology vol. 52,3 (1973): 233-5. doi: https://doi.org/10.1104/pp.52.3.233
Riov J, Jaffe MJ. Cholinesterases from Plant Tissues: II. Inhibition of Bean Cholinesterase by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride (AMO-1618). Plant Physiol. 1973 Sep;52(3):233-5. doi: 10.1104/pp.52.3.233. PMID: 16658537; PMCID: PMC366475.
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Plant Physiol. 1973 Sep;52(3):233-5. doi: 10.1104/pp.52.3.233.

Cholinesterases from Plant Tissues: II. Inhibition of Bean Cholinesterase by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride (AMO-1618).

Plant physiology

J Riov, M J Jaffe

Affiliations

  1. Department of Botany, Ohio University, Athens, Ohio 45701.

PMID: 16658537 PMCID: PMC366475 DOI: 10.1104/pp.52.3.233

Abstract

2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine carboxylate methyl chloride (AMO-1618) inhibits the activity of a cholinesterase isolated from mung bean (Phaseolus aureus) roots at concentrations comparable to those which retard growth and inhibit development of secondary roots of bean seedlings. Fifty per cent inhibition of the cholinesterase activity occurred at 0.21 mm. Inhibition of the cholinesterase is non-competitive and irreversible. The growth retardant seems to be a specific cholinesterase inhibitor since it has no effect on non-choline esterases.

References

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