Display options
Share it on

Plant Physiol. 1975 Jun;55(6):1057-61. doi: 10.1104/pp.55.6.1057.

Photoaffinity-labeled Auxins: Synthesis and Biological Activity.

Plant physiology

N J Leonard, J C Greenfield

Affiliations

  1. School of Chemical Sciences, University of Illinois, Urbana, Illinois 61801.

PMID: 16659209 PMCID: PMC541765 DOI: 10.1104/pp.55.6.1057

Abstract

Two light-sensitive analogs of 2,4-dichlorophenoxyacetic acid, namely 4-azido-2-chlorophenoxyacetic acid and 3-azido-5-chlorophenoxyacetic acid, have been synthesized for use as auxin photoaffinity labels. The preparation and biological activity of the compounds are described. Both contain the photolabile azido group; the 2,4-substituted compound shows auxin activity and the 3,5-substituted compound does not. These photoaffinity analogs of 2,4-dichlorophenoxyacetic acid may be useful in the identification of the auxin receptor molecules in plant cells and eventually of the receptor sites within these molecules.

References

  1. Biochemistry. 1974 Jul 2;13(14):2986-94 - PubMed
  2. J Biol Chem. 1971 Jul 25;246(14):4477-84 - PubMed
  3. Nat New Biol. 1973 Mar 28;242(117):127-8 - PubMed
  4. J Am Chem Soc. 1973 Jul 25;95(15):5072-3 - PubMed
  5. Nat New Biol. 1972 Nov 22;240(99):111-3 - PubMed
  6. Biochemistry. 1973 Oct 9;12(21):4085-92 - PubMed
  7. Biochemistry. 1969 Nov;8(11):4431-6 - PubMed
  8. Proc Natl Acad Sci U S A. 1969 Jul;63(3):897-903 - PubMed
  9. Proc Natl Acad Sci U S A. 1972 Nov;69(11):3146-50 - PubMed
  10. Biochemistry. 1973 Oct 9;12(21):4079-84 - PubMed
  11. Biochem J. 1972 Jul;128(3):499-508 - PubMed
  12. J Biol Chem. 1966 Jan 25;241(2):421-7 - PubMed

Publication Types