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Cooney RV, Mumma RO, Benson AA. Arsoniumphospholipid in algae. Proc Natl Acad Sci U S A. 1978;75(9):4262-4doi: 10.1073/pnas.75.9.4262.
Cooney, R. V., Mumma, R. O., & Benson, A. A. (1978). Arsoniumphospholipid in algae. Proceedings of the National Academy of Sciences of the United States of America, 75(9), 4262-4. https://doi.org/10.1073/pnas.75.9.4262
Cooney, R V, et al. "Arsoniumphospholipid in algae." Proceedings of the National Academy of Sciences of the United States of America vol. 75,9 (1978): 4262-4. doi: https://doi.org/10.1073/pnas.75.9.4262
Cooney RV, Mumma RO, Benson AA. Arsoniumphospholipid in algae. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4262-4. doi: 10.1073/pnas.75.9.4262. PMID: 16592562; PMCID: PMC336092.
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Proc Natl Acad Sci U S A. 1978 Sep;75(9):4262-4. doi: 10.1073/pnas.75.9.4262.

Arsoniumphospholipid in algae.

Proceedings of the National Academy of Sciences of the United States of America

R V Cooney, R O Mumma, A A Benson

Affiliations

  1. Marine Biology Research Division, Scripps Institution of Oceanography, La Jolla, California 92093.

PMID: 16592562 PMCID: PMC336092 DOI: 10.1073/pnas.75.9.4262

Abstract

A novel phospholipid containing arsenic was formed by all marine algae cultured in [(74)As]arsenate. Components of the labeled algal extracts readily separated by two-dimensional paper radiochromatography. Base-catalyzed deacylation of the major lipid yielded a phosphodiester identical to one of the two major water-soluble compounds. Acid or enzymic hydrolysis of the phosphodiester produced a product identified as trimethylarsoniumalactic acid. The structure of the phospholipid therefore is O-phosphatidyltrimethylarsoniumlactic acid. Detoxication of arsenate by marine algae leads to accumulation of the arsoniumphospholipid as a major reservoir for arsenic. Its degradation to trimethylarsoniumbetaine, dimethylarsinic acid, methanearsonic acid, and arsenate in marine food chains and its metabolism in human beings are of considerable interest.

References

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  4. Acta Chem Scand. 1973;27(5):1586-94 - PubMed
  5. Nature. 1972 Nov 3;240(5375):44-5 - PubMed

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