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Watanakunakorn C. Cycloserine Induction, Propagation, and Antimicrobial Susceptibility of Wall-Defective Staphylococcus aureus. Infect Immun. 1971;3(3):438-43doi: 10.1128/iai.3.3.438-443.1971.
Watanakunakorn, C. (1971). Cycloserine Induction, Propagation, and Antimicrobial Susceptibility of Wall-Defective Staphylococcus aureus. Infection and immunity, 3(3), 438-43. https://doi.org/10.1128/iai.3.3.438-443.1971
Watanakunakorn, C. "Cycloserine Induction, Propagation, and Antimicrobial Susceptibility of Wall-Defective Staphylococcus aureus." Infection and immunity vol. 3,3 (1971): 438-43. doi: https://doi.org/10.1128/iai.3.3.438-443.1971
Watanakunakorn C. Cycloserine Induction, Propagation, and Antimicrobial Susceptibility of Wall-Defective Staphylococcus aureus. Infect Immun. 1971 Mar;3(3):438-43. doi: 10.1128/iai.3.3.438-443.1971. PMID: 16557993; PMCID: PMC416171.
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Infect Immun. 1971 Mar;3(3):438-43. doi: 10.1128/iai.3.3.438-443.1971.

Cycloserine Induction, Propagation, and Antimicrobial Susceptibility of Wall-Defective Staphylococcus aureus.

Infection and immunity

C Watanakunakorn

Affiliations

  1. Infectious Disease Division, Department of Internal Medicine, University of Cincinnati College of Medicine and the Cincinnati General Hospital, Cincinnati, Ohio 45229.

PMID: 16557993 PMCID: PMC416171 DOI: 10.1128/iai.3.3.438-443.1971

Abstract

A method of induction of L colonies of Staphylococcus aureus by cycloserine, the propagation of wall-defective staphylococci (WDS), and the development and antimicrobial susceptibility of stable WDS are presented. The growth and morphology of the cycloserine-induced L colonies and WDS were indistinguishable from those induced by methicillin or lysostaphin. The antimicrobial susceptibility of the stable cycloserine-induced WDS was similar to that of the stable methicillin-induced and lysostaphin-induced WDS by both broth dilution and agar diffusion techniques. A survey of the English literature reveals that wall-defective bacteria are always resistent to antimicrobial agents which inhibit cell wall synthesis (cycloserine, penicillins, and cephalosporins). They are virtually all susceptible to antimicrobial agents which have other modes of action. The susceptibility to vancomycin and bacitracin varied from study to study.

References

  1. Arch Intern Med. 1960 May;105:668-74 - PubMed
  2. Biochim Biophys Acta. 1965 Feb 15;97:242-50 - PubMed
  3. J Gen Microbiol. 1963 Nov;33:325-34 - PubMed
  4. Proc Natl Acad Sci U S A. 1965 Apr;53:881-9 - PubMed
  5. J Bacteriol. 1965 Feb;89:415-20 - PubMed
  6. Biochemistry. 1964 Apr;3:471-80 - PubMed
  7. Proc Natl Acad Sci U S A. 1964 Mar;51:414-21 - PubMed
  8. J Bacteriol. 1962 Sep;84:508-12 - PubMed
  9. Nature. 1962 Oct 13;196:195-6 - PubMed
  10. J Gen Microbiol. 1962 Jul;28:559-69 - PubMed
  11. Nature. 1959 Dec 12;184(Suppl 24):1894-5 - PubMed
  12. Proc Soc Exp Biol Med. 1958 Jan;97(1):132-5 - PubMed
  13. Antimicrob Agents Chemother (Bethesda). 1968;8:382-7 - PubMed
  14. Antimicrob Agents Chemother (Bethesda). 1965;5:339-44 - PubMed
  15. J Bacteriol. 1969 May;98(2):347-50 - PubMed
  16. J Gen Microbiol. 1967 Feb;46(2):299-304 - PubMed
  17. J Gen Microbiol. 1969 Jan;55(1):155-9 - PubMed
  18. Proc Soc Exp Biol Med. 1967 Feb;124(2):611-5 - PubMed
  19. J Lab Clin Med. 1966 Oct;68(4):543-51 - PubMed
  20. J Bacteriol. 1964 May;87(5):1044-50 - PubMed
  21. J Bacteriol. 1969 May;98(2):749-55 - PubMed
  22. J Infect Dis. 1970 Feb;121(2):124-8 - PubMed
  23. Proc Natl Acad Sci U S A. 1965 Jul;54(1):75-81 - PubMed
  24. Proc Natl Acad Sci U S A. 1965 Oct;54(4):1133-41 - PubMed
  25. J Infect Dis. 1969 Jan;119(1):67-74 - PubMed
  26. J Infect Dis. 1966 Apr;116(2):221-30 - PubMed

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