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Dowd PS, Kelleher J, Walker BE, et al. Nutritional and immunological assessment of patients with anorexia nervosa. Clin Nutr. 1983;2(2):79-83doi: 10.1016/0261-5614(83)90037-7.
Dowd, P. S., Kelleher, J., Walker, B. E., & Guillou, P. J. (1983). Nutritional and immunological assessment of patients with anorexia nervosa. Clinical nutrition (Edinburgh, Scotland), 2(2), 79-83. https://doi.org/10.1016/0261-5614(83)90037-7
Dowd, P S, et al. "Nutritional and immunological assessment of patients with anorexia nervosa." Clinical nutrition (Edinburgh, Scotland) vol. 2,2 (1983): 79-83. doi: https://doi.org/10.1016/0261-5614(83)90037-7
Dowd PS, Kelleher J, Walker BE, Guillou PJ. Nutritional and immunological assessment of patients with anorexia nervosa. Clin Nutr. 1983 Jul;2(2):79-83. doi: 10.1016/0261-5614(83)90037-7. PMID: 16829414.
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Clin Nutr. 1983 Jul;2(2):79-83. doi: 10.1016/0261-5614(83)90037-7.

Nutritional and immunological assessment of patients with anorexia nervosa.

Clinical nutrition (Edinburgh, Scotland)

P S Dowd, J Kelleher, B E Walker, P J Guillou

Affiliations

  1. Department of Surgery, Clinical Sciences Building, St James's University Hospital, Leeds LS9 7TF UK.

PMID: 16829414 DOI: 10.1016/0261-5614(83)90037-7

Abstract

The nutritional and immunological status of patients with anorexia nervosa was assessed. Anthropometric measurements were found to be lowered as were the serum levels of zinc (p<0.01), copper (p<0.01) and ceruloplasmin (p<0.05) in comparison with the control group. However the serum levels of albumin, pre-albumin, transferrin and retinol binding protein, vitamins A and D and leucocyte vitamin C were generally found to be within normal limits. Lymphocyte transformation was measured in response to stimulation with the mitogens Con A, PHA and PWM. Responses were normal in all patients with the exception of one who showed a depressed response to Con A. Natural killer cell activity was measured against the target cell line K562 and was not found to differ significantly from controls. It is suggested that the relatively normal protein and vitamin status is responsible for maintaining the apparently normal cellular immune function in patients with anorexia nervosa.

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