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Berrettini W. Bipolar disorder and schizophrenia: not so distant relatives?. World Psychiatry. 2003;2(2):68-72
Berrettini, W. (2003). Bipolar disorder and schizophrenia: not so distant relatives?. World psychiatry : official journal of the World Psychiatric Association (WPA), 2(2), 68-72.
Berrettini, Wade. "Bipolar disorder and schizophrenia: not so distant relatives?." World psychiatry : official journal of the World Psychiatric Association (WPA) vol. 2,2 (2003): 68-72.
Berrettini W. Bipolar disorder and schizophrenia: not so distant relatives?. World Psychiatry. 2003 Jun;2(2):68-72. PMID: 16946898; PMCID: PMC1525081.
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World Psychiatry. 2003 Jun;2(2):68-72.

Bipolar disorder and schizophrenia: not so distant relatives?.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Wade Berrettini

Affiliations

  1. Department of Psychiatry, University of Pennsylvania, 415 Curie Blvd., Philadelphia, PA 19104, USA.

PMID: 16946898 PMCID: PMC1525081

Abstract

Bipolar disorder (BPD) and schizophrenia (SZ) may have some susceptibility genes in common, despite the fact that current nosology separates them into non-overlapping categories. The evidence for shared genetic factors includes epidemiologic characteristics, family studies and overlap in confirmed linkages. Review of these data indicates that there are five genomic regions which may represent shared genetic susceptibility of BPD and SZ. As the genes underlying these confirmed linkages are identified, the current nosology must be changed to reflect the new knowledge concerning the shared etiologies of BPD and SZ.

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