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World Psychiatry. 2003 Oct;2(3):172-8.

Symptom dimensions and outcome in schizophrenia.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Raimo K R Salokangas

Affiliations

  1. Department of Community Health and Epidemiology, Abramsky Hall, Queen’s University, Kingston, Ontario, K7L 3N6, Canada.

PMID: 16946931 PMCID: PMC1525103

Abstract

Since Kraepelin, outcome has been one of the most frequently used criteria for testing the validity of diagnosis in psychiatry. Factor analytic methods have showed, however, that the symptomatology of psychiatric patients can be divided into symptom dimensions, which also correlate with outcome. The aim of the present study was to explore how diagnostic sub-categories and symptom dimensions correlate with outcome in first-episode and chronic patients with schizophrenia. In samples of first-episode schizophrenia patients (n=156) and chronic schizophrenia patients (n=1571), symptom variables were factored and the five symptom dimensions obtained were correlated with outcome variables. In both samples, symptom dimensions were more powerful in explaining variance of outcome than categorical sub-diagnoses. Thus, a dimensional approach seems to be valuable not only in describing the illness picture, but also in predicting outcome in schizophrenia.

References

  1. Br Med J. 1980 Jan 12;280(6207):66-8 - PubMed
  2. Nord J Psychiatry. 2002;56(5):319-27 - PubMed
  3. Acta Psychiatr Scand. 1986 Jun;73(6):609-17 - PubMed
  4. Arch Gen Psychiatry. 1976 Jun;33(6):766-71 - PubMed
  5. J Affect Disord. 1998 Mar;48(2-3):171-80 - PubMed
  6. Br J Psychiatry. 1987 Aug;151:145-51 - PubMed
  7. J Abnorm Psychol. 1989 Feb;98(1):62-70 - PubMed
  8. Br J Psychiatry. 1992 Sep;161:335-43 - PubMed
  9. Acta Psychiatr Scand. 1997 Jan;95(1):32-9 - PubMed
  10. Schizophr Bull. 1985;11(3):471-86 - PubMed
  11. Am J Psychiatry. 1997 Mar;154(3):371-7 - PubMed
  12. Schizophr Bull. 1985;11(3):440-52 - PubMed
  13. Arch Gen Psychiatry. 1982 Jul;39(7):789-94 - PubMed
  14. Acta Psychiatr Scand. 1989 Aug;80(2):187-93 - PubMed
  15. Acta Psychiatr Scand Suppl. 1978;(271):5-27 - PubMed
  16. Am J Psychiatry. 1994 Jun;151(6 Suppl):144-54 - PubMed
  17. Psychol Med. 1989 May;19(2):365-82 - PubMed
  18. Arch Gen Psychiatry. 1964 Nov;11:509-18 - PubMed
  19. Psychopathology. 1986;19(1-2):50-9 - PubMed
  20. Schizophr Bull. 1990;16(3):537-45 - PubMed
  21. J Nerv Ment Dis. 1959 Nov;129:450-66 - PubMed
  22. J Nerv Ment Dis. 1994 Nov;182(11):631-8 - PubMed
  23. Schizophr Res. 1990 Oct-Dec;3(5-6):333-45 - PubMed
  24. Br J Psychiatry. 1992 Feb;160:179-86 - PubMed
  25. Br J Psychiatry. 1983 Feb;142:145-51 - PubMed
  26. Arch Gen Psychiatry. 1974 Jul;31(1):37-42 - PubMed
  27. Acta Psychiatr Scand. 1978 Oct;58(4):327-38 - PubMed
  28. Arch Gen Psychiatry. 1995 May;52(5):352-60 - PubMed
  29. Monogr Gesamtgeb Psychiatr Psychiatry Ser. 1986;41:1-295 - PubMed
  30. Arch Gen Psychiatry. 1995 May;52(5):341-51 - PubMed
  31. Br J Psychiatry. 1991 Mar;158:317-22 - PubMed
  32. J Nerv Ment Dis. 1994 Apr;182(4):193-204 - PubMed
  33. Psychiatry Res. 1992 Nov;44(2):153-65 - PubMed
  34. Psychiatr Q. 1949 Apr;23(2):248-76 - PubMed

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