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Puttemans ML, Dryon L, Massart DL. Extraction of organic acids by ion-pair extraction with tri-n-octylamine - VIII. Identification of synthetic dyes in pharmaceutical preparations. J Pharm Biomed Anal. 1985;3(6):503-10doi: 10.1016/0731-7085(85)80068-6.
Puttemans, M. L., Dryon, L., & Massart, D. L. (1985). Extraction of organic acids by ion-pair extraction with tri-n-octylamine - VIII. Identification of synthetic dyes in pharmaceutical preparations. Journal of pharmaceutical and biomedical analysis, 3(6), 503-10. https://doi.org/10.1016/0731-7085(85)80068-6
Puttemans, M L, et al. "Extraction of organic acids by ion-pair extraction with tri-n-octylamine - VIII. Identification of synthetic dyes in pharmaceutical preparations." Journal of pharmaceutical and biomedical analysis vol. 3,6 (1985): 503-10. doi: https://doi.org/10.1016/0731-7085(85)80068-6
Puttemans ML, Dryon L, Massart DL. Extraction of organic acids by ion-pair extraction with tri-n-octylamine - VIII. Identification of synthetic dyes in pharmaceutical preparations. J Pharm Biomed Anal. 1985;3(6):503-10. doi: 10.1016/0731-7085(85)80068-6. PMID: 16867642.
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J Pharm Biomed Anal. 1985;3(6):503-10. doi: 10.1016/0731-7085(85)80068-6.

Extraction of organic acids by ion-pair extraction with tri-n-octylamine - VIII. Identification of synthetic dyes in pharmaceutical preparations.

Journal of pharmaceutical and biomedical analysis

M L Puttemans, L Dryon, D L Massart

Affiliations

  1. Farmaceutisch Instituut, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.

PMID: 16867642 DOI: 10.1016/0731-7085(85)80068-6

Abstract

Synthetic dyes were extracted from syrups, oral suspensions, tablets, gelatin capsules, suppositories and granules by ion-pair formation with tri-n-octylamine (TnOA) and back-extracted with perchlorate ions. Identification was performed by TLC on cellulose layers and by reversed phase ion-pair HPLC.

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