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Cavina G, Valvo L, Alimenti R. Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC. J Pharm Biomed Anal. 1985;3(6):535-46doi: 10.1016/0731-7085(85)80071-6.
Cavina, G., Valvo, L., & Alimenti, R. (1985). Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC. Journal of pharmaceutical and biomedical analysis, 3(6), 535-46. https://doi.org/10.1016/0731-7085(85)80071-6
Cavina, G, et al. "Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC." Journal of pharmaceutical and biomedical analysis vol. 3,6 (1985): 535-46. doi: https://doi.org/10.1016/0731-7085(85)80071-6
Cavina G, Valvo L, Alimenti R. Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC. J Pharm Biomed Anal. 1985;3(6):535-46. doi: 10.1016/0731-7085(85)80071-6. PMID: 16867645.
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J Pharm Biomed Anal. 1985;3(6):535-46. doi: 10.1016/0731-7085(85)80071-6.

Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC.

Journal of pharmaceutical and biomedical analysis

G Cavina, L Valvo, R Alimenti

Affiliations

  1. Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

PMID: 16867645 DOI: 10.1016/0731-7085(85)80071-6

Abstract

A reversed-phase high-performance liquid chromatographic method was developed for the assay of medroxyprogesterone acetate and for the detection and determination of related steroids present as impurities in the drug. The method was compared with the normal-phase technique of the USP XX and was also applied to the analysis of tablets and injectable suspensions.

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