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Gross A, Joutsiniemi SL, Rimon R, et al. Correlation of symptom clusters of schizophrenia with absolute powers of main frequency bands in quantitative EEG. Behav Brain Funct. 2006;2:23doi: 10.1186/1744-9081-2-23.
Gross, A., Joutsiniemi, S. L., Rimon, R., & Appelberg, B. (2006). Correlation of symptom clusters of schizophrenia with absolute powers of main frequency bands in quantitative EEG. Behavioral and brain functions : BBF, 223. https://doi.org/10.1186/1744-9081-2-23
Gross, Andres, et al. "Correlation of symptom clusters of schizophrenia with absolute powers of main frequency bands in quantitative EEG." Behavioral and brain functions : BBF vol. 2 (2006): 23. doi: https://doi.org/10.1186/1744-9081-2-23
Gross A, Joutsiniemi SL, Rimon R, Appelberg B. Correlation of symptom clusters of schizophrenia with absolute powers of main frequency bands in quantitative EEG. Behav Brain Funct. 2006 Jun 29;2:23. doi: 10.1186/1744-9081-2-23. PMID: 16808844; PMCID: PMC1564142.
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Behav Brain Funct. 2006 Jun 29;2:23. doi: 10.1186/1744-9081-2-23.

Correlation of symptom clusters of schizophrenia with absolute powers of main frequency bands in quantitative EEG.

Behavioral and brain functions : BBF

Andres Gross, Sirkka-Liisa Joutsiniemi, Ranan Rimon, Björn Appelberg

Affiliations

  1. Helsinki University Central Hospital, Department of Psychiatry, Välskärinkatu 12 A, 00260 Helsinki, Finland. [email protected]

PMID: 16808844 PMCID: PMC1564142 DOI: 10.1186/1744-9081-2-23

Abstract

BACKGROUND: Research of QEEG activity power spectra has shown intriguing results in patients with schizophrenia. Different symptom clusters have been correlated to QEEG frequency bands. The findings have been to some extent inconsistent. Replication of the findings of previous research is thus an important task. In the current study we investigated the correlations between the absolute powers of delta, theta, alpha, and beta frequency bands over the fronto-central scalp area (FC) with the PANSS subscales and the Liddle's factors in 16 patients with schizophrenia.The authors hypothesised a priori the correlations reported by Harris et al (1999) of PANSS negative subscale with delta power, Liddle's psychomotor poverty with delta and beta powers, disorganisation with delta power and reality distortion with alpha power on the midline FC.

METHODS: The sample consisted of 16 patients with chronic schizophrenia considered as having insufficient clinical response to conventional antipsychotic treatment and evidencing a relapse. The correlations between quantitative electroencephalography (QEEG) absolute powers of delta (1.5-3.0 Hz), theta (3.0-7.5 Hz), alpha (7.5-12.5 Hz), and beta (12.5-20.0 Hz) frequency bands over the fronto-central scalp area (FC) with PANSS subscales and Liddle's factors (reality distortion, disorganisation, psychomotor poverty) were investigated.

RESULTS: Significant positive correlations were found between the beta and psychomotor poverty (p < 0.05). Trends towards positive correlations (p < 0.1) were observed between delta and PANSS negative subscale and psychomotor poverty. Alpha did not correlate with reality distortion and delta did not correlate with disorganisation.Post hoc analysis revealed correlations of the same magnitude between beta and psychopathology generally over FC.

CONCLUSION: The a priori hypothesis was partly supported by the correlation of the beta and psychomotor poverty. Liddle's factors showed correlations of the same magnitude with PANSS subscales. Supplementary analysis showed beta frequency correlating non-specifically over FC with a wide range of psychiatric symptomatology in patients with schizophrenia having a relapse.

References

  1. Neurology. 1997 Jul;49(1):277-92 - PubMed
  2. Eur Arch Psychiatry Clin Neurosci. 1992;241(6):328-32 - PubMed
  3. Am J Psychiatry. 1990 Nov;147(11):1457-62 - PubMed
  4. Arch Gen Psychiatry. 1987 Jun;44(6):514-7 - PubMed
  5. J Clin Neurophysiol. 2001 Jan;18(1):9-13 - PubMed
  6. Biol Psychiatry. 1988 Feb 1;23(3):295-311 - PubMed
  7. Biol Psychiatry. 1972 Aug;5(1):1-13 - PubMed
  8. Biol Psychiatry. 2001 Jul 15;50(2):108-16 - PubMed
  9. J Clin Psychopharmacol. 1993 Oct;13(5):332-42 - PubMed
  10. Psychopharmacologia. 1966;8(5):309-18 - PubMed
  11. Eur Neuropsychopharmacol. 1990 Nov;1(1):27-36 - PubMed
  12. J Neuropsychiatry Clin Neurosci. 1999 Spring;11(2):190-208 - PubMed
  13. Cereb Cortex. 2004 Jan;14(1):91-6 - PubMed
  14. Biol Psychiatry. 1994 Dec 15;36(12):801-26 - PubMed
  15. Pharmacopsychiatry. 1993 Nov;26(6):254-8 - PubMed
  16. Psychiatry Res. 1996 May 31;67(1):49-58 - PubMed
  17. Pharmacopsychiatry. 2004 May;37(3):119-22 - PubMed
  18. Int J Neurosci. 2001 Apr;107(3-4):265-78 - PubMed
  19. Psychol Med. 1987 Feb;17(1):49-57 - PubMed
  20. Psychiatry Res. 1989 Aug;29(2):137-49 - PubMed
  21. Brain Topogr. 1992 Spring;4(3):207-13 - PubMed
  22. Schizophr Bull. 1987;13(2):261-76 - PubMed
  23. Psychol Med. 1999 Sep;29(5):1175-81 - PubMed

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