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Symonds HW, Treacher RJ. The experimental induction of hypophosphataemia in goats using anion exchange columns. J Physiol. 1967;193(3):619-29doi: 10.1113/jphysiol.1967.sp008382.
Symonds, H. W., & Treacher, R. J. (1967). The experimental induction of hypophosphataemia in goats using anion exchange columns. The Journal of physiology, 193(3), 619-29. https://doi.org/10.1113/jphysiol.1967.sp008382
Symonds, H W, and Treacher, R J. "The experimental induction of hypophosphataemia in goats using anion exchange columns." The Journal of physiology vol. 193,3 (1967): 619-29. doi: https://doi.org/10.1113/jphysiol.1967.sp008382
Symonds HW, Treacher RJ. The experimental induction of hypophosphataemia in goats using anion exchange columns. J Physiol. 1967 Dec;193(3):619-29. doi: 10.1113/jphysiol.1967.sp008382. PMID: 16992300; PMCID: PMC1365517.
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J Physiol. 1967 Dec;193(3):619-29. doi: 10.1113/jphysiol.1967.sp008382.

The experimental induction of hypophosphataemia in goats using anion exchange columns.

The Journal of physiology

H W Symonds, R J Treacher

PMID: 16992300 PMCID: PMC1365517 DOI: 10.1113/jphysiol.1967.sp008382

Abstract

1. Inorganic phosphate was selectively removed from the circulating blood of five anaesthetized goats by means of columns of anion-exchange resin. Concentrations of other ions were unaffected by the column.2. Rates of inorganic phosphate extraction in excess of 5 m-moles/hr caused a fall in plasma inorganic phosphate of up to 50% in 30 min.3. In four of the goats the calculated inorganic phosphate mobilization rate rose sharply to a maximum between 5.8 and 12.7 m-moles/hr and then fell progressively as more phosphate was removed.4. During the course of the experiments a fall in blood pressure occurred, accompanied by a rise in blood glucose. The reasons for this are discussed.

References

  1. J Clin Invest. 1946 Mar;25(2):158-71 - PubMed
  2. Nature. 1963 Oct 12;200:181 - PubMed
  3. J Clin Pathol. 1963 Jan;16:18-24 - PubMed

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